Fatty acid amide

Results: 17



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1

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase Benjamin F. Cravatt*†, Kristin Demarest*, Matthew P. Patricelli*, Michael H. Bracey*, Dan K. Giang

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- Date: 2008-05-12 15:27:38
    2Chemistry / Biochemistry / Biology / Cannabinoids / Fatty acid amide hydrolase / Substrate / Anandamide / Endocannabinoid system / Chemical biology / Monoacylglycerol lipase / Metabolism / Taurine

    Biochemistry 2004, 43, Assignment of Endogenous Substrates to Enzymes by Global Metabolite Profiling† Alan Saghatelian, Sunia A. Trauger, Elizabeth J. Want, Edward G. Hawkins, Gary Siuzdak, and

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    Language: English - Date: 2008-05-12 15:27:38
    3Chemistry / Biology / Biochemistry / Membrane biology / Cannabinoids / Neurotransmitters / Fatty acid amide hydrolase / Substrate / Methoxy arachidonyl fluorophosphonate / Anandamide / Cell membrane / Amino acid

    REPORTS and a HexNAc residue, suggesting that the glycan in the m/z⫹ glycopeptide was linked to the peptide through HexNAc rather than DATDH (Fig. 4C, inset). In view of the DATDH synthesis pathway (19), it is l

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    Language: English - Date: 2008-05-12 15:27:39
    4Biology / Chemistry / Genomics / Proteins / Avidin / Glycoproteins / Biotinylation / Biotin / Activity-based proteomics / Serine hydrolase / Chemical biology / Fatty acid amide hydrolase

    Biochemistry 2001, 40, Profiling Serine Hydrolase Activities in Complex Proteomes† Dana Kidd,‡ Yongsheng Liu,‡ and Benjamin F. Cravatt*

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    Language: English - Date: 2008-05-12 15:27:39
    5Chemistry / Neurochemistry / Biochemistry / Cannabinoids / G protein coupled receptors / Fatty acid amides / Fatty acid amide hydrolase / Alcohols / Endocannabinoid system / Anandamide / Cannabinoid receptor type 2 / Cannabinoid receptor type 1

    Functional disassociation of the central and peripheral fatty acid amide signaling systems Benjamin F. Cravatt*†, Alan Saghatelian*, Edward G. Hawkins*, Angela B. Clement*, Michael H. Bracey*, and Aron H. Lichtman‡ *

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    Language: English - Date: 2008-05-12 15:27:36
    6Chemistry / Neurochemistry / Cannabis / Cannabinoids / Fatty acid amides / Endocannabinoids / Lipids / Neurotransmitters / Fatty acid amide hydrolase / Anandamide / URB597 / Endocannabinoid system

    doi:S1367

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    Language: English - Date: 2008-05-12 15:27:37
    7Proteins / Genomics / Proteomics / Bioinformatics / Peripheral membrane proteins / Activity-based proteomics / Urokinase / Chemical biology / Benjamin Cravatt III / Fatty acid amide hydrolase / Lipase / Clusterin

    Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness Nadim Jessani, Yongsheng Liu, Mark Humphrey, and Benjamin F. Cravatt* The Skaggs Institute for Chemical Biology and Depa

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    Language: English - Date: 2008-05-12 15:27:36
    8Chemical reactions / Functional groups / Hydrolases / Catalysis / Fatty acid amide hydrolase / Amidase / Substrate / Serine hydrolase / Benjamin Cravatt III / Enzyme catalysis / Amide / Acyl group

    Biochemistry 1999, 38, 14125 Fatty Acid Amide Hydrolase Competitively Degrades Bioactive Amides and Esters through a Nonconventional Catalytic Mechanism†

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    Language: English - Date: 2008-05-12 15:27:39
    9Cannabinoids / Fatty acid amides / Endocannabinoids / Neurochemistry / Biomolecules / Fatty acid amide hydrolase / URB597 / Anandamide / Endocannabinoid system / Palmitoylethanolamide / Methoxy arachidonyl fluorophosphonate / Benjamin Cravatt III

    -441–448$20.00 THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS Copyright © 2004 by The American Society for Pharmacology and Experimental Therapeutics JPET 311:441–448, 2004 Vol. 311, No.

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    Language: English - Date: 2008-05-12 15:27:36
    10Medicinal chemistry / Metabolism / Fatty acid amide hydrolase / Enzyme inhibitor / Chemical biology / Benjamin Cravatt III / Substrate / Acetylcholinesterase / Protease inhibitor / Activity-based proteomics / Methoxy arachidonyl fluorophosphonate

    © 2003 Nature Publishing Group http://www.nature.com/naturebiotechnology LETTERS Discovering potent and selective reversible inhibitors of enzymes in complex proteomes

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    Language: English - Date: 2008-05-12 15:27:37
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