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Protein folding / Energy landscape / Alpha helix / Downhill folding / Protein structure / Biology / Folding funnel


PERSPECTIVES maining fixed in one of many structures, unable to reconfigure to the lowest energy crystal state. At temperatures far above a glass transition, a rough landscape is easily Peter G. Wolynes, Jose N. Onuchic,
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Document Date: 2012-03-06 07:35:36


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City

La Jolla / San Diego / /

Company

Eaton / /

Country

United States / /

Facility

University Onuchic / College Park / University of Maryland / /

IndustryTerm

energy minimum / ficult search / energy landscape / deep valleys folding search / linear free energy reCole / energy decrease folding / energy landscape topography / unguided search / lowest energy crystal state / free-energy state / energy decrease / complicated energy / flat energy landscape / energy et al. / free energy landscape / rugged energy flow / configurational energy landscape quence mutation / short search / energy / protein energy landscape / /

Organization

National Science Foundation / Institute for Physical Sciences / University of Maryland / College Park / Department of Physics / School of Chemical Sciences / /

Person

Jose N. Onuchic / Peter G. Wolynes / /

ProvinceOrState

Maryland / Illinois / California / /

Technology

thermodynamics / lasers / real protein Technology / simulation / /

URL

www.sciencemag.org / /

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