Back to Results
First PageMeta Content
Transcription factors / MicroRNA / Calorie restriction / Diets / CRTC1 / Sir2 / Huntingtin / CREB / Sirtuin / Biology / Enzymes / Proteins


LETTERS Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway npg
Add to Reading List

Document Date: 2014-05-17 09:29:19

Open Document

File Size: 600,65 KB

Share Result on Facebook

City

La Jolla / Cambridge / PGC / Charlestown / BSKO / Santa Cruz / /

Company

F. Glenn Laboratory / IgG / Novartis / Peptide Biology Laboratories / L.J. & Gygi S.P. / LI-COR Biosciences / Millipore / Developmental Studies Hybridoma Bank / Agilent / G. & Guarente L.P. / Sarbassov D.D. / Bio-Rad Laboratories / Sirt1 / Jackson Laboratories / B. PrimerBank / Covance / J. Comp / Nature America Inc. / M.C. & Guarente L.P. / /

Country

United States / /

/

Event

FDA Phase / Product Issues / /

Facility

Massachusetts General Hospital / Salk Institute / University of Cambridge / Massachusetts Institute of Technology / MassGeneral Institute / Scripps Research Institute / /

IndustryTerm

online version / ONLINE METHODS npg / transcriptional networks / energy balance / neuron-restrictive silencing factor binding site / advance online publication / /

MedicalCondition

hyperinsulinemia / H.Y. Diseases / autosomal dominant disease / Huntington’s disease / amyotrophic lateral sclerosis / inherited neurodegenerative disorder / Polyglutamine diseases / MS / abnormal movements / mitochondrial dysfunction / brain pathology / insulin resistance / disease / polyglutamine disorders / hypothermia / early Huntington’s disease / profound hypothermia / full-length Huntington’s disease / Parkinson’s disease / diseases / infection / deficiency / human disease / /

NaturalFeature

Mt HTT / HTT Mt / /

Organization

Harvard Medical School / MassGeneral Institute for Neurodegenerative Disease / Hereditary Disease Foundation / Massachusetts General Hospital Subcommittee on Research Animal Care / Harvard / Massachusetts General Hospital / Salk Institute / Massachusetts Institute of Technology / Glenn Foundation for Medical Research / Department of Neurology / University of Cambridge / Scripps Research Institute / Committee on Animal Care / /

Person

Nat / John R Yates / /

Position

cto / Light Cycler / Nestin-Cre driver / 18S forward / AUTHOR / Singer / NATURE MEDICINE Reporter / reporter / /

Product

Tao / Sirt1 / TORC1 / /

ProgrammingLanguage

FP / /

ProvinceOrState

California / Massachusetts / /

Technology

Proteomics / antibodies / directed mutagenesis / modified SEQUEST algorithm / Cell Signaling / Multidimensional Protein Identification Technology / DNA binding / HTML / Cell Signaling Technology / Prolucid algorithm / DNA Chip / gene expression / DNA sequencing / 100 ChIP / 3g / /

URL

http /

SocialTag