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Transcription factors / Hepatology / Metabolism / Dicarboxylic acid / Fatty acid metabolism / Peroxisome proliferator-activated receptor gamma / Beta oxidation / Fatty liver / Peroxisome proliferator-activated receptor alpha / Biology / Fatty acids / Intracellular receptors


Cell Reports Article The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty Acids
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Document Date: 2013-10-29 08:51:02

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File Size: 2,97 MB

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Geneva / Canton de Vaud / Krarup / Lausanne / Lille / /

Company

acyl-CoA / Agilent Technologies / Summers S.A. / Sigma-Aldrich / Creative Commons / FAs / Suzuki / Provimi Kliba AG / MCFAs / Alteon Inc. / /

Country

Switzerland / France / /

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pence / /

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Event

FDA Phase / Extinction / /

Facility

Northwestern University / University of Geneva / Nanyang Technological University / Metabolic Evaluation Facility of Center / University of Lausanne / Hall et al. / /

IndustryTerm

coconut oil consumption / stock solution / in vivo bioluminescence imaging system / coconut oil overaccumulate / downstream product / oil / degradation products / coconut oil feeding / coconut oil / enzymatic products / energy / food shift / food complement / coconut oil high-fat / lipid peroxidation products / degradation product / diabetes treatment / measured using an in vivo bioluminescence imaging system / /

MedicalCondition

inflammatory reaction / liver inflammation / seizures / liver failure / coma / massive inflammation / massive nutrient-induced inflammation / MCAD deficiency / liver tumors / acute hypoketotic hypoglycemia / increased fibrosis / inflammatory cells / hypoglycemia / HFD-CO. Fulminant Liver Failure / liver steatosis / insulin resistance / inflammatory and fibrotic response / inflammatory cytokines genes / disease / liver diseases / non-alcoholic fatty liver disease / diabetes / lethargy / metabolic syndrome / tumor necrosis / hepatic failure / C12DCA-Supplemented Normal Chow Induces Liver Failure / inflammation / inflammatory cytokines tumor necrosis / acute liver disease / inflammatory / fibrosis / /

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J.K. / /

Organization

National Institute of Health / University of Geneva / Veterinary Office / Nanyang Technological University / Singapore / Northwestern University / Chicago / Center for Integrative Genomics / National Centre of Competence / United Nations / Universite´ Lille Nord de France / US Federal Reserve / Switzerland 3Swiss Institute for Bioinformatics / European Union / Swiss National Science Foundation / University of Lausanne / Lausanne / USA 5Lee Kong Chian School of Medicine / /

Person

Marianne Carrard / Nat / Hashimoto / Jun Ding / Johan Auwerx / Catherine Moret / Van Roermund / Isabelle Riezman / Van Veldhoven / /

Position

G.P. / original author / transactivation assay using Gal4-ligand binding domain-luciferase reporter / polar head / PPRE-luciferase reporter / representative / reporter / /

Product

Sigma / isoflurane / Col1a1 / S2F / /

ProvinceOrState

Illinois / North Carolina / Northern Territory / /

PublishedMedium

PLoS ONE / /

Technology

alpha / Genomics / Bioinformatics / Molecular modeling / siRNA / antibodies / apoptosis / Cell Signaling Technology / gene expression / http / performed using antibodies / /

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http /

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