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Programmed cell death / Transcription factors / Peptide hormones / Obesity / Peroxisome proliferator-activated receptor gamma / Adipocyte / Insulin / Adipose tissue / Tumor necrosis factor-alpha / Biology / Cell biology / Apoptosis


TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma
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Document Date: 2013-01-24 09:58:55

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City

Epalinges / Dallas / Freiburg / Mu¨nchen / Munich / Heidelberg / Grenzach / Wiesbaden / Hamburg / Rockford / San Jose / Santa Cruz / Hilden / Helsinki / Mu¨nster / Gruenberg / Darmstadt / /

Company

Research and Arts / Sigma Aldrich / Amersham / mCi / Qiagen / Biomers.net / Berg SA / BD Biosciences / Stephens / IgG / Baden-Wuerttemberg Ministry of Science / Ligand / ApoTech Corporation / ViraPower Lentiviral Expression Systems / Olympus Optical Co. / Lodish HF. / Systat Software GmbH Inc. / HP / Creative Commons / Macmillan Publishers Limited / /

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Switzerland / Netherlands / Germany / United States / /

Currency

pence / /

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Event

FDA Phase / /

Facility

M Federici TRAIL / Although TRAIL / Ulm University / As TRAIL / University Medical Center Ulm / University of Ulm / Yet TRAIL / TRAIL R2 / Disease TRAIL / Wang S. TRAIL / University of Texas Southwestern Medical Center / ng/ml TRAIL / /

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IndustryTerm

cancer therapy / Cell culture media / aB47 kDa cleavage product / energy imbalance / energy / unknown cleavage product / energy intake / treatment of cancer / chemicals / acute and chronic energy imbalance / survival machinery / cleavage product / chronic and acute energy imbalance / energy balance / treatment of obesity / /

MedicalCondition

JE / Eckel J. Tumor necrosis / local inflammation / rheumatoid arthritis / colitis ulcerosa / thereby causing insulin resistance / Chronic inflammation / chronic and acute energy imbalance / In obesity / enhanced islet inflammation / obesity-linked insulin resistance / type 2 diabetes mellitus / tumor / hepatic inflammation / cancer / tumors / advanced solid tumors / Adipose tissue insulin resistance / Goldkorn T. Tumor / diabetes / genetic obesity / diseases / systemic inflammation / inflammatory pathways / p80 tumor necrosis / Simpsom Golabi Behmel syndrome / inflammatory cytokines / TNFa-induced insulin resistance / obesity / obesity-related insulin resistance / MS / TRAIL deficiency / several cancer / necrosis factor / adipose tissue inflammation / streptozotocin-induced diabetes / insulin resistance / necrosis / Disease / obesity-induced insulin resistance / advanced cancer / PFA / Tumor necrosis / obesity-related systemic insulin resistance / diabetes mellitus / obesity-related inflammation / acute and chronic energy imbalance / diet-induced obesity / /

MedicalTreatment

plastic surgery / cancer therapy / anticancer therapy / intravenous infusion / /

Organization

University of Texas Southwestern Medical Center / Dallas / Pediatric Endocrinology / Diabetes and Obesity Unit / Institutional Animal Care and Use Committee / German Research Association / European Social Fund / Touchstone Diabetes Center / US Federal Reserve / Baden-Wuerttemberg Ministry of Science / Research and Arts / University of Ulm / Czech MP / Division of Pediatric Endocrinology / Department of Pediatrics and Adolescent Medicine / Ulm University / Division of Pediatric Endocrinology and Diabetes / /

Person

Alexandra Killian / Ann Oncol / Susann Baumgart / Konrad D. Fas / Ann Clin / Mol Med / Van Parijs / /

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Position

player in the development / important player / Keller MP / representative / Germany *Corresponding author / /

Product

FS / Sigma / R2 / R1 / H1 / TRAIL / ETR2 / Apo2L/TRAIL / /

Technology

digital camera / human genome / apoptosis / DNA Chip / gene expression / treating cancer / recombination / alpha / antibodies / Biotechnology / Cell Signaling / DNA binding / /

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http /

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