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Chemical pathology / Gamma-glutamyl transpeptidase / Cisplatin / Glutathione / Cell culture / Carboplatin / GGT / Chemistry / Alkylating antineoplastic agents / Ammine complexes


Controversial Role of Gamma-Glutamyl Transferase Activity in Cisplatin Nephrotoxicity Lukas Fliedl 1, Matthias Wieser 1, Gabriele Manhart 1, Matthias P. Gerstl 1, Abdulhameed Khan 2, Johannes Grillari 2,3 and Regina Gril
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City

Santos / ANPEP / Helsinki / Nanodrop / Weinheim / L. A. / Vienna / London / /

Company

Brown / Grainger / Sigma Aldrich / Russell / Wiley-VCH Verlag GmbH & Co. KGaA / Biotechnology University of Natural Resources / Life Sciences Vienna / Evercyte GmbH / Life Sciences Vienna Muthgasse 18 1190 Vienna Austria / Windass A. S. / Methuen & Co. Ltd. / Proc Natl Acad Sci U S A / /

Country

Germany / Austria / United Kingdom / /

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Facility

University of Natural Resources / General Hospital of Vienna / Pflugers Arch / /

IndustryTerm

test systems / stock solution / suitable model systems / pharmaceutical / pharmaceuticals / in vitro nephrotoxicity model systems / model systems / in vitro toxicity prediction systems / nephrotoxicity model systems / chemicals / /

MedicalCondition

ovarian cancer / lymphoma / melanoma / injury / cancers / human papilloma virus E6/E7 genes / tumor / cancer / tumors / disease / kidney failure / acute kidney failures / diseases / fibroma / deficiency / /

MedicalTreatment

chemo / antibiotics / chemotherapy / /

OperatingSystem

Dos / /

Organization

General Hospital of Vienna / University of Natural Resources and Life Sciences Vienna / European Union / /

Person

Cherry / Regina Grillari / Matthias P. Gerstl / Gabriele Manhart / Regina Grillari-Voglauer / Gallagher / Holder / Johannes Grillari / Arch Toxicol / Matthias Wieser / /

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Position

D. J. / RT / R. N. / King / real-time cycler / /

Product

carboplatin / Cisplatin / Sigma / acetic acid / glycine / /

ProvinceOrState

Tirol / British Columbia / New Mexico / M. B. / /

Technology

toxicogenomics / siRNA / Biotechnology / drug screening / drug discovery / gene expression / chemotherapy / http / GGT assay The protocol / drug development / /

URL

http /

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