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LETTER doi:[removed]nature11287 A restricted cell population propagates glioblastoma growth after chemotherapy
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Document Date: 2012-10-11 10:35:20


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Dallas / Santa Cruz / /

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Macmillan Publishers Limited. / Vector Laboratories / Millipore / CSC / Adobe Systems Incorporated / BD Biosciences / Jackson Labs / Olympus / Roche Pharmaceuticals / /

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United States / /

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IDR / /

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FDA Phase / /

Facility

Rosalind Franklin University / Cancer Prevention Research Institute of Texas / Columbia University / University of Texas Southwestern Medical Center / /

IndustryTerm

online version / ml kg21 stock solution / Cancer Prevention / cancer treatment / In vivo chemical administration / /

MedicalCondition

endogenous glioma models / vestigial tumours / single human melanoma / solid tumours / high-grade gliomas / hindbrain tumours / putative endogenous glioma stem cell / glioma progression / common primary malignant brain tumour / intractable disease / human tumors / novel tumours / treated tumours / murine tumours / astrocytomas / GCV-treated Mut7;Nes-DTK tumours / endogenous murine gliomas / cell-like glioma cells / Mut7;Nes-DTK-GFP gliomas / cortical tumours / glioblastoma / tumor / endogenous tumours / cancer / Infiltrative malignant gliomas / residual TMZ/GCV-treated tumours / rare cancer / classic glioma feature / only vestigial tumours / GCVtreated tumours / malignant glioma / also developed gliomas / glioblastoma multiforme cells / TMZ/GCVresistant hindbrain tumours / herpes simplex virus / GCV Glioblastoma multiforme / high grade astrocytomas / tumours / Mut7;NesDTK tumours / significantly smaller tumours / Malignant astrocytomas / large tumours / endogenous glioma cells / untreated control tumours / both tumours / GFP-expressing glioma cell population gives / chronic ganciclovir administration / glioma / Mut7;Nes-DTKGFP tumours / herpes / Primary gliomas / untreated tumours / gliomas / both dorsal and ventral tumours / glioblastoma growth / Such tumours / pure astrocytic tumours / glioblastoma multiforme patients7 / somatic tumor / glioblastoma multiforme / dorsal tumours / oligodendroglioma / tumour / cancer stem cells / endogenous glioma tumour cells / p53 tumor / malignant astrocytoma / untreated gliomas / L. F. Malignant glioma / malignant gliomas / residual tumours / ventral tumours / /

MedicalTreatment

Radiotherapy / chemotherapy / gene therapy / /

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A. D. / /

Organization

University of Texas Southwestern Medical Center / Dallas / Rosalind Franklin University / Institutional Animal Care and Use Committee / TMZ administration / Columbia University / New York / University of Texas Southwestern Medical Center at Dallas / Goldhirsh Foundation / Department of Developmental Biology / Department of Pediatrics / James S. McDonnell Foundation / Cancer Prevention Research Institute of Texas / Aves Lab / Developmental Biology & Kent Waldrep Center for Basic Research / Department of Pathology and Cell Biology / GCV administration / /

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Gene Ther / Nissl / Vega / /

Position

Cancer Society Research Professor / Author Information Reprints / Author / Representative / Illustrator / Singer / /

Product

IdU injection / Sigma / Cytovene / BrdU injection / TMZ injection / ganciclovir / IdU / /

ProvinceOrState

New York / Texas / P. N. / /

Technology

Genotyping / stem cells / drug delivery / chemotherapy / genomics / Drug-delivery / antibodies / transplantation / gene therapy / /

URL

www.nature.com/nature / www.nature.com/reprints / /

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