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DNA repair / Transcription factors / Genetics / V(D)J recombination / Recombination activating gene / HMGB1 / Non-homologous end joining / RAGE / DNA / Biology / Immune system / Lymphocytes


PNAS PLUS Single-molecule analysis of RAG-mediated V(D)J DNA cleavage Geoffrey A. Lovelya,b, Robert C. Brewsterb,c, David G. Schatzd, David Baltimoreb,1, and Rob Phillipsa,b,c,1 a
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Document Date: 2015-03-23 14:55:15


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File Size: 2,25 MB

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City

Pasadena / Destainville / New Haven / /

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EntertainmentAwardEvent

Director’s Pioneer Award / /

Facility

Howard Hughes Medical Institute / N terminus of RAG1 / Paired Complex / Mayo Clinic College of Medicine / RSS Complex / C terminus of RAG2 / California Institute of Technology / 2c complex / University of California / /

IndustryTerm

nonhomologous end joining machinery / 23RSS site / 12RSS binding site / 23RSS binding site / reagents/analytic tools / 12RSS site / downstream product / metal ion dependent / target site / local alignment search tool / recombination-activating gene products / /

Organization

California Institute of Technology / National Institute of Health / Caltech’s Protein Expression Center / Yale University School of Medicine / Mayo Clinic College of Medicine / Sackler Foundation / University of California / Los Angeles / Howard Hughes Medical Institute / Los Angeles Joint Center for Translational Medicine / /

Person

Laurence Salome / Arch Immunol Ther Exp (Warsz) / Patrick Swanson / Pierre Gilles de Gennes / Jesse Bloom / Rob Phillipsa / David G. Schatzd / Michael Anaya / Jeff Gelles / Jim Maher / David Baltimore / Geoffrey A. Lovelya / David Baltimoreb / Pradeep Ramesh / Stephanie Johnson / Robert C. Brewsterb / Martin Linden / Jin Lee / Philippe Rousseau / L. James Maher / Catherine Tardin / /

Position

Author / Director / /

ProgrammingLanguage

K / /

ProvinceOrState

California / /

PublishedMedium

PLoS ONE / /

Technology

cell receptors / DNA binding / recombination / /

URL

www.pnas.org/cgi/doi/10.1073/pnas.1503477112 / www.pnas.org/lookup/suppl/doi / /

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