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Protein methods / Protein-protein interaction assays / Signal transduction / Glyceraldehyde 3-phosphate dehydrogenase / Green fluorescent protein / Förster resonance energy transfer / Phosphoinositide phospholipase C / Transfection / Nuclear membrane / Biology / Cell biology / Fluorescent dyes


Phospholipase Cε Hydrolyzes Perinuclear Phosphatidylinositol 4-Phosphate to Regulate Cardiac Hypertrophy Lianghui Zhang,1,4 Sundeep Malik,1,4 Jinjiang Pang,3 Huan Wang,2,5 Keigan M. Park,1 David I. Yule,1 Burns C. Blaxa
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Document Date: 2013-05-30 13:12:34

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File Size: 1,27 MB

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City

GST / /

Company

YFP PLC / Ab EpacI PLC / perinuclear PLC / mAKAPscaffolded PLC / CON ET-1 NE PLC / Ryr2 PLC / siRNA YFP PLC / Ctl PLC / Ctl siRNA PLC / Gaq-Dependent Hypertrophy Requires mAKAP-Bound PLC / YFP Gq Ctl siRNA YFP Gq PLC / cardiomyocyte PLC / Hypertrophy PLC / mAKAP-Bound PLC / PKD S916 130 130 PKD PLC / Cre+ WT Neo PLC / cpTOME 70 50 PLC / purified PLC / NRVM PLC / mAKAP No Ab / mAKAP-Scaffolded PLC / Elsevier Inc. / GAPDH (fold change) B PLC / /

Currency

pence / CFP / /

/

Facility

PLCε-Ryr2 scaffolding / Cincinnati Children’s Hospital Medical Center / scaffolding of Epac1 / Institute of Cardiovascular Research University / Scaffolding of PLCε / Wistar Institute / NE Scaffolding / NE scaffolding of PLCε / Ryr2 scaffolding / PLCε scaffolding / /

IndustryTerm

treatment of heart failure / ratio imaging epifluorescence microscopy / nuclear-targeted fluorescence resonance energy transfer / /

MedicalCondition

cardiac hypertrophy / INTRODUCTION Heart failure / contraction / inflammatory functions / heart failure / interstitial fibrosis / infection / high blood pressure / fibrosis / /

Organization

Wistar Institute / National Institute of Health / University of Rochester School of Medicine and Dentistry / Cincinnati Children’s Hospital Medical Center / Epac1 association / NE PLC / Biochemistry and Biophysics 3Aab Institute / /

Person

Cocco / Alan V / /

Position

driver / Prime Minister / similar PM / Singer / prominent PM / MP / DAG reporter / representative / PLCε messenger / reporter / kinase activity reporter / /

Product

Fura-2 / PI4P / Golgi PI4P / cpTOME 60 Relative Fluorescence Relative Fluorescence 70 1.10 / PIP2 / nifedipine / /

ProvinceOrState

Nebraska / /

Technology

gene expression / genotyping / /

URL

http /

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