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Gene expression / Molecular genetics / Epigenetics / Protein domains / RNA-induced transcriptional silencing / Heterochromatin / RNA interference / Kinetochore / Centromere / Biology / Genetics / RNA


Molecular Cell Article High-Affinity Binding of Chp1 Chromodomain to K9 Methylated Histone H3 Is Required to Establish Centromeric Heterochromatin
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Document Date: 2012-04-16 08:31:02


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File Size: 1,13 MB

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City

Elgin / Findley / Taverna / Briggs / Bungtown / Proudfoot / Tolia / /

Company

H3K9me / Ligand / DelPhi / Gygi S.P. / Elsevier Inc. / Jacobs S.A. / Peptide Protein Research Ltd. / Cold Spring Harbor Laboratory / /

Country

United Kingdom / /

Currency

pence / /

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Event

Product Issues / /

Facility

Howard Hughes Medical Institute / RITS complex / Structural Biology Laboratory / Stony Brook University / University of Kentucky / Jude Children’s Research Hospital / N terminus / Chp1 Chromodomain/H3K9me3 Complex The complex / Cohesin complex / /

IndustryTerm

machinery / binding site / open binding site / search model / /

Organization

National Institute of Health / Cancer Center / H3K9me association / Centromeric Heterochromatin Thomas Schalch / 1 / 4 Godwin Job / 2 / 4 Victoria J. Noffsinger / 2 / 4 / 5 Sreenath Shanker / 2 Canan Kuscu / 1 / 3 Leemor Joshua-Tor / 1 / * and Janet F. Partridge2 / * 1Keck Structural Biology Laboratory / Chp1’s association / Department of Energy / Stony Brook University / Jude Children’s Research Hospital / University of Kentucky / H3K9me2 association / Chp1-H3K9me association / Swi6 association / Chp1 association / Howard Hughes Medical Institute / Chp1 Mutants Show Reduced Centromeric Association / office of Basic Energy Sciences / /

Person

Nat / /

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Position

investigator / cen /

Product

clr4+ reintroduction / Chp1 mutants / Chp1 Mutants Are Deficient / association / other strains / Chp1 Localization / backgrounds / chp1 Mutant Strains Surprisingly / /

ProgrammingLanguage

R / /

ProvinceOrState

New Jersey / Aurora / South Dakota / South Carolina / New Hampshire / New York / /

Technology

siRNA / antibodies / Dus / DNA binding / ion exchange / crystallization / /

URL

http /

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