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Company Baxter / Enzon / / IndustryTerm early candidate products / hemoglobin solution / acellular hemoglobin solution / chemical modifications / / MedicalCondition Chest pain / experimental pancreatitis / Coagulation disorder / duodenal ulcer / Cerebrovascular accident / nausea / monoparesis / thrombocytopenia / anaphylaxis / edematous pancreatitis / hemiplegia / transient ischemic attack / esophageal spasm / Ischemic injury / hemiparesis / septic shock / reflex bradycardia / pulmonary edema / bradycardia / Cardiac arrest / Chest pain/chest tightness / pneumonitis / Sepsis / cardiac / cardiac failure / purpura / abdominal pain / aspiration pneumonia / Congestive heart failure / Pneumonia / hemolytic anemia / pulmonary embolus / Hemorrhage/bleeding/anemia / hypertension / cardiopulmonary arrest / thrombocythemia / respiratory failure / gastric ulcer / cerebral infarction / dyspnea / patchy parenchymal necrosis / dysphagia / malignant hypertension / Kidney Diseases / Cardiac arrhythmias / deep venous thrombosis / mild inflammation / oliguria / Stroke / postoperative hypertension / thromboembolism / ileus / Pulmonary Hypertension / pain / vomiting / systolic hypertension / secondary anemia / Myocardial infarction / postoperative nausea / pancreatitis / chest tightness / Ventricular fibrillation / spasm / renal failure / acute pancreatitis / thrombosis / inflammatory form / Acute renal failure / Anemia / Respiratory distress / / MedicalTreatment blood transfusion / surgery / resuscitation / Thoracic and Cardiovascular Surgery / / Organization Blood Products Advisory Committee / office of Blood Research / FDA / / Person Ann Surg / Robert M. Winslow / Alayash / Toby Silverman / Laurence Landow / Ann Hematol / Hon Sum Ko / Kimberly Lindsey / / Position General / / Product Metab Rev 31 / / ProgrammingLanguage C * / / ProvinceOrState ARDS / / PublishedMedium British Journal of Anaesthesia / Military Medicine / / Technology polymerization / / URL www.fda.gov / www.northfieldlabs.com / www.fda.gov/ohrms/dockets/ac/cber06.html#BloodProducts / /
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Review of Publicly Available Reports of Adverse Events Associated with HBOCs Toby Silverman, M.D., Laurence Landow, M.D., Hon Sum Ko, M.D., and Kimberly Lindsey, M.D. Office of Blood Research and Review, CBER, FDA April