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Neuron Article Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits Guomei Tang,1 Kathryn Gudsnuk,2 Sheng-Han Kuo,1 Marisa L. Cotrina,3,7 Gorazd Rosoklija,4,8 Alexander Sosunov,3
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Document Date: 2014-12-29 21:14:10

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auditory and visual processing / social brain network / functional imaging / postsynaptic site / cortical-cortical and cortical-subcortical communications / brain networks / /

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autism spectrum disorders / both disease / integrated Neuron Autism / brain dysfunction / Tsc deficiency / disease / neuronal autophagy deficiency / autism / INTRODUCTION Autism spectrum disorders / either Neuron Autism / neurofibromatosis / seizure / autophagy deficiency / X syndrome / basal neuronal Neuron Autism / tuberous sclerosis / higher Neuron Autism / clinical syndrome / infection / deficiency / /

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Friedman Brain Institute / Icahn School of Medicine / University of Rochester / Rochester / USA 8New York State Psychiatric Institute / Pharmacology Columbia University Medical Center / /

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soma / social behaviors / rapamycin-normalized pS6 levels / Mouse Models / preference / Cortical Projection Neurons / social novelty preferences / mice / sociability / autophagy / /

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