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City Stockholm / Citrate / / Company FMC / HP / Fresenius Medical Care / / Country Sweden / / Currency HKD / / / Facility Pamela Youde Nethersole Eastern Hospital / The University of Hong Kong / Queen Mary Hospital / / IndustryTerm complicated solution / prepared citratecontaining replacement solution / citrate-based continuous renal replacement therapy protocol / treatment systems / et al. Online CHDF system / replacement solution / possible solutions / dialysate solution / energy / Energy gain / treatment technology / practicable protocol / citrate solution / mL/h prefilter citrate containing replacement solution / trisodium citrate solution / default solution / online replacement fluid / mL/h post-filter replacement solution / concentrated citrate solution / calcium-citrate product / / MedicalCondition vascular hypotonia / metabolic alkalosis / Torsades de pointes / acidosis / liver failure / endotoxemia / cirrhosis / thrombocytopenia / cardiac arrhythmia / critical illness / sepsis / ventricular arrhythmia / hypotension / carpopedal spasm / chronic liver disease / ischaemic hepatitis / acute kidney injury / metabolic acidosis / tetany / inflammation / / MedicalTreatment blood transfusion / liver transplant / venovenous hemofiltration / hemodialysis / hemodiafiltration / dialysis / renal replacement therapy / / Organization Department of Medicine / University of Hong Kong / Centre Multi Single Single Single Multi Single / Department of Intensive Care / Pamela Youde Nethersole Eastern Hospital / Queen Mary Hospital / / Person Chin Med / Pamela Youde Nethersole / / Position Gibney RT / Corresponding author / / Product Sodium bicarbonate / Dextrose / Ci-Ca Dialysate K4 Plus 133 4 / Cl / Ci-Ca Dialysate K2 Plus 133 2 / Conclusion Citrate / / PublishedMedium PLoS One / / Technology citrate-based continuous renal replacement therapy protocol / pharmacokinetics / treatment technology / target-orientated algorithm / dialysis / / URL www.hkmj.org / / SocialTag 
Review Article Risks and benefits of citrate anticoagulation for continuous renal replacement therapy HP Shum *, WW Yan, TM Chan