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Neurological disorders / Brain tumor / Neurofibroma / Schwannomatosis / Neurofibromin 1 / Merlin / Glioblastoma multiforme / Vestibular schwannoma / Cancer stem cell / Medicine / Oncology / Health


CONFERENCE REPORT What’s New in Neurofibromatosis? Proceedings From the 2009 NF Conference: New Frontiers Joseph L. Kissil,1 Jaishri O. Blakeley,2 Rosalie E. Ferner,3 Susan M. Huson,4 Michel Kalamarides,5 Victor-Felix
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Document Date: 2012-08-29 16:39:36


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City

Cincinnati / Portland / Eppendorf / Washington / Hamburg / Rio de Janeiro / Mexico City / Boston / Sydney / KISSIL ET / Paris / Philadelphia / Salt Lake City / Vancouver / Baltimore / New York / London / /

Company

NF1 / Wiley InterScience / CLINICAL FEATURES AND MANAGEMENT / Fox Chase / NexGenix Pharmaceuticals / McCormick / Novartis / Ó 2010 Wiley-Liss Inc. / Biobank / NHS Trust / /

Country

United Kingdom / Denmark / Switzerland / Netherlands / France / Australia / Germany / United States / /

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Event

FDA Phase / Product Issues / /

Facility

University of British Columbia / Cincinnati Children’s Hospital Medical Center / University of Texas Southwestern / Children’s Hospital of Philadelphia / Science University / Ohio University / University of Sydney / The Children’s Hospital / University of Kansas / University of Michigan / Children’s National Medical Center / Eppendorf University / University of California / University of Iowa / Massachusetts General Hospital / Kennedy Krieger Institute / University of Oklahoma / Germany Children’s National Medical Center / Erasmus University / Johns Hopkins University / Mary’s Hospital / University of Manchester / University of Alabama / laboratory of John Kyriakis / Children’s Hospital / University Sydney / Leibniz Institute / Harvard Medical School/Massachusetts General Hospital / New York Medical College / National Cancer Institute / Women’s Hospital / laboratory of Frances Hannan / Wistar Institute / Tufts University / Peninsula College / University of Pennsylvania / Inserm U674 University / /

IndustryTerm

expression systems / food / similar shock-odor protocol / post-transcriptional processing / natural product / natural products / treatment protocols / tumor site / volumetric analysis imaging / e-au / injection site / study protocol / pharmaceutical / established associative learning protocol / /

MedicalCondition

progressive vestibular schwannomas / several tumor / symptomatic plexiform neurofibromas / vestibular schwannoma growth / human schwannoma gene expression / human melanoma / primary central nervous system tumors / dermal neurofibroma tumors / benign plexiform neurofibroma / minor pruritus / Astrocytomas / chronic inflammation / spinal neurofibromatosis / human MPNST / regional plexiform tumors / brain tumors / optic pathway glioma / tumor / In glioblastoma / electric shock / malignant peripheral nerve sheath tumor / autosomal dominant disorders / internal tumors / human primary schwannoma / Neurofibromatosis / schwannoma cells / discrete neurofibromas / velopharyngeal insufficiency / plexiform tumors / malignant astrocytomas / solitary sporadic tumors / recurrent malignant peripheral nerve sheath tumors / vascular inflammatory cells / fibromas / meningioma modeling / human cancers / meningiomas / benign and malignant peripheral nerve sheath tumor / neurofibromas / solitary / sporadic schwannomas / hearing loss / benign and malignant peripheral nerve sheath tumors / meningioma mouse model / MPNST / peripheral schwannomas / disease / rhabdoid tumors / INTRODUCTION Neurofibromatosis / symptomatic disease / meningioma cell / very aggressive and invasive soft tissue sarcomas / often debilitating tumors / pain / schwannomas / actively proliferating tumor / benign nerve tumors / severe neurofibroma burden / cancer stem cell / schwannoma pathophysiology / subsequent vascular disease / unilateral vestibular schwannomas / progressive plexiform neurofibromas / Legius syndrome / NF2-deficient Schwannoma / dermal tumors / vestibular schwannoma specimens / meningioma subtypes / melanoma / sporadic / solitary schwannomas / learning disabilities / xenograft tumors / neurofibroma / larval learning system pairing shock / progressive low-grade gliomas / NF2 patient tumors / recurrent MPNSTs / internal tumor / hereditary and multiple schwannoma syndromes / cancer / attention deficit disorders / tumors / malignant peripheral nerve sheath tumors / benign and malignant tumors / ependymoma / human cancer / MPNSTs / peripheral nerve schwannoma / primary MPNSTs / vestibular schwannoma / Merlindeficient human meningioma / MPNST tumor / brainstem tumors / NF1 dermal neurofibromas / tinnitus / neural tumors / sporadic MPNSTs / advanced disease / meningioma / speech disorder / spinal nerve schwannoma / metastasis / NF2 meningioma / spinal schwannomas / radiographically progressive disease / plexiform neurofibromas / human meningiomas / astrocytoma formation / bilateral vestibular schwannomas / schwannoma subtypes / pruritus / prospective plexiform neurofibroma studies / NF2-associated meningiomas / dermal neurofibromas / cancers / dermal and optic glioma tumors / necrosis / different tumor / neurofibroma development / neurofibromatosis-associated vestibular schwannomas / schwannoma transcription profiles / myeloid disease / chronic progressive hearing loss / malignant astrocytoma / high-grade astrocytomas / different schwannomas / schwannoma formation / benign schwannomas / merlin’s tumor / dehydration / NF2 tumor / /

MedicalTreatment

surgery / chemotherapy / treatment protocols / photodynamic therapy / drug therapies / drug therapy / /

Organization

St Thomas’ NHS Trust / University of Sydney / University of Michigan / Cincinnati Children’s Hospital Medical Center / NF / University of California / San Francisco / University of Texas Southwestern / Harvard Medical School / Leibniz Institute for Age Research / National Cancer Institute / Ohio University / University of Pennsylvania / Germany Children’s National Medical Center / University of Manchester / Manchester / Johns Hopkins University / Harvard School of Public Health / Oregon Health & Science University / Hopital Beaujon / Peninsula College for Medicine and Dentistry / Tumor Foundation / University of Kansas / University of Iowa / NHS / Eppendorf University / Hamburg / University of Alabama at Birmingham / Wistar Institute / University of Oklahoma / Kennedy Krieger Institute / New York Medical College / Women’s Hospital / Massachusetts General Hospital / Children’s Hospital Boston / Tufts University / Children’s Hospital / National Medical Center / Erasmus University / Children’s Tumor Foundation / University of British Columbia / /

Person

Steven Scherer / Gareth Evans / Harry Miao / Jonathan Payne / Susan Huson / Jan Manent / John Mulvihill / Kimberly Jett / Joseph L. Kissil / Andre Bernards / Pablo Hollstein / Vijaya Ramesh / Myelinating Schwann / Nancy Ratner / Johanna Buchstaller / Yuan Zhu / Michel Kalamarides / Sean Morrison / Gordon Harris / Kathryn North / Alcino Silva / Ramesh V / Geoffrey Kilili / Nicole Ullrich / Jan Friedman / Sheila Alcantara / Andrew B. Gladden / C. Oliver Hanemann / Bruce Korf / Ian McCutcheon / Luis Parada / Brigitte Widemann / Mila McCurrach / Kim Hunter-Schaedle / Linnea Vose / Larry Sherman / Frank McCormick / Scott Plotkin / Emmanuelle di Tomaso / Michael Fisher / Brendan Manning / Ronen Marmorstein / Victor-Felix Mautner / Roger Packer / Jonathan Chernoff / Faris Farassati / Madeleine Duvic / Lou Chang / Helen Morrison / Allan Belzberg / Andrea McClatchey / Betty Chow / Sheryl Rimrodt / Walter J. Jessen / Zachary Morris / Rachael Hornigold / Karen Cichowski / /

Position

novel mediator / driver / /

Product

doxycycline / Lovastatin / simvastatin / Ranibizumab injection / PTC299 / NF1 / Neurofibromatosis / basal cell polarity / KISSIL ET AL / /

ProvinceOrState

British Columbia / Utah / California / Newfoundland / Pennsylvania / Iowa / Massachusetts / Alabama / New York / Washington / Michigan / District of Columbia / Oklahoma / Kansas / Oregon / /

Technology

radiation / X-ray / DRUG SCREENING / apoptosis / hpo / DNA Chip / chemotherapy / gene targeting / treatment protocols / genotype / study protocol / antibodies / cell signaling / laser / stem cells / gene expression / transplantation / MRI / similar shock-odor protocol / associative learning protocol / tested using a similar shock-odor protocol / /

URL

www.interscience.wiley.com / www.ctf.org / /

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