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Interferon / Molecular cloning / Recombinant DNA / Fusion protein / Interferon alfa / CXCL11 / Biology / Cytokines / Antivirals


Construction of a Novel Liver-Targeting Fusion Interferon by Incorporation of a Plasmodium Region I-Plus Peptide
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City

Carlsbad / Burlingame / Novagen / Bradford / Guangzhou / Cape Cod / Mannheim / Ni2+ / Article / /

Company

IgG / Thermo Fisher / GenBank / Takara / Agilent / pET / CSP (GenBank accession no. X15363) BioMed Research International / Creative Commons / GE healthcare / Da-An Gene Co. / Guangdong Provincial Key Laboratory / Bio-Rad / DNA Star Inc. / Hindawi Publishing Corporation / designed using DNA Star / /

Country

Germany / Japan / United States / China / /

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Event

FDA Phase / /

Facility

Guangzhou Higher Education Mega Center / Guangdong Pharmaceutical University / N terminus / Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances / /

IndustryTerm

hepatitis B therapy / real-time fluorescence / pharmaceutical potential / sucrose solution / immobilized metal ion affinity chromatography / 2b / metal coordination / healthcare / physical/chemical modification / control / buffer systems / gene fusion technology / gene product / 2b using gene fusion technology / homogeneous product / treatment of hepatitis B / therapeutic applications / /

MedicalCondition

HBV / AIDS-related Kaposi’s sarcoma / alopecia / hepatitis B / melanoma / infectious viral particles / fatigue / serious depression / chronic myeloid lymphoma / autoimmune disorders / several cancers / chronic viral hepatitis / HBV infection / hepatoma cell line HepG / Viral Hepatitis / influenza-like syndrome / viral liver infections / vesicular stomatitis virus / chronic hepatitis B / /

MedicalTreatment

dialysis / /

MusicGroup

BioMed Research International / /

Organization

Guangdong Pharmaceutical University / School of Basic Courses / Administration of IFN / Use Committee / Guangzhou Higher Education Mega Center / /

Person

Alexa Fluor / Thomas Minor / /

Position

Academic Editor / Major / /

Product

penicillin / sodium chloride / guanidine hydrochloride / Sigma / ampicillin / Intova IC-12 Digital Camera / Ni / sodium pentobarbital / HisTrap / DH5a / /

ProvinceOrState

South Dakota / Guangdong Province / /

PublishedMedium

Applied and Environmental Microbiology / Nature Reviews Microbiology / The Pediatric Infectious Disease Journal / The Journal of Clinical Investigation / Nucleic Acids Research / /

Technology

alpha / Protein Engineering / TaqMan technology / genetic engineering / antibodies / Biotechnology / gene fusion technology / cloning / Pharmacokinetics / gene cloning / 2b using gene fusion technology / gel electrophoresis / dialysis / /

URL

http /

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