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Chemistry / Enantiopure drugs / Medicine / Imipenem / Pyrrolidines / Ertapenem / Thienamycin / Beta-lactamase / Cilastatin / Carbapenem antibiotics / Organic chemistry / Microbiology


Document Date: 2009-03-31 14:11:33

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Company

MERCK & CO. Inc. / Ames / /

Event

FDA Phase / /

Facility

Adverse Laboratory Changes Adverse laboratory / Laboratory Tests While PRIMAXIN I.V. / /

IndustryTerm

antimicrobial drug product / chemical name / /

MedicalCondition

polyuria / glossitis / difficile associated diarrhea / Gynecologic infections / Pseudomonas / Morganella morganii Proteus vulgaris Providencia rettgeri Pseudomonas / Skin Rash Irritation / aeruginosa infections / myoclonus / joint infections / headache / common cold / Seizures / leukopenia / hallucinations / focal tremors / nausea / thrombocytopenia / serious infections / non-CNS infections / toxic epidermal necrolysis / hyperhidrosis / mixed infections / Stevens-Johnson syndrome / tremor / CNS disorders / respiratory tract infections / skin structure infections / Cardiovascular System Phlebitis / encephalopathy / Skin infections / erythema multiforme / pruritus vulvae / tachycardia / diarrhea / hypersensitivity / chronic pulmonary disease / Urinary tract infections / Interactions Generalized seizures / hepatitis / cystic fibrosis / Intra-abdominal infections / hearing loss / documented underlying CNS disorder / pruritus / infections / polyarthralgia / seizure disorders / agranulocytosis / confusional states / hypotension / fatal colitis / abdominal pain / pneumonia / hemolytic anemia / monobacterial infections / thrombophlebitis / OCCASIONALLY FATAL HYPERSENSITIVITY / bacterial infections / flushing / Bacterial septicemia / gastroenteritis / dyspnea / Carcinogenesis / neutropenia / candidiasis / oliguria / vertigo / Phlebitis / Erythema / azotemia / fever / superinfection / septicemia / seizure / viral infections / hemorrhagic colitis / vomiting / S. aureus / urticaria / hepatic failure / bacterial infection / diseases / Endocarditis / stomach cramps / mild diarrhea / Polymicrobic infections / infection / Increased ALT / hyperventilation / clinical infections / dizziness / anuria / lower respiratory tract infections / depression / meningitis / rash / pseudomembranous colitis / paresthesia / acute renal failure / tinnitus / pancytopenia / angioneurotic edema / /

MedicalTreatment

antibiotics / Intravenous infusion / hemodialysis / /

Organization

Pediatric Use / and DOSAGE AND ADMINISTRATION / DOSAGE AND ADMINISTRATION / /

Position

physician / PRECAUTIONS General / /

Product

probenecid / penicillin / Intravenous Injection / S-028 Page / sodium bicarbonate / PRIMAXIN / S-065 NDA / IMIPENEM AND CILASTATIN FOR INJECTION / ganciclovir / EPINEPHRINE / to / imipenem / S-065 / /

ProvinceOrState

South Dakota / /

Technology

pharmacokinetics / DNA synthesis / /

SocialTag