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Chemistry / Enzymes / Indoleamine 2 / 3-dioxygenase / Tumor necrosis factor-alpha / RIPK1 / Apoptosis / Ido / Tryptophan / Biology / Immune system / Cell biology


Citation: Cell Death and Disease[removed], e437; doi:[removed]cddis[removed] & 2012 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis Necrostatin-1 analogues: critical issues on the
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Document Date: 2012-11-29 06:00:04


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File Size: 2,72 MB

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City

Kunzendorf / Boston / Lyngby / Jung / Vilvoorde / Genest / Stuttgart / Norwich / Diegem / Igepal / San Diego / Erembodegem / St. Louis / /

Company

Nec / Roche Diagnostics Belgium N.V. / Comark Electronics / Sigma Aldrich / Amersham / GraphPad Software Inc. / mCi / Merck / Cox / BD Bioscience Benelux N.V. / Odyssey LI-COR Biosciences GmbH / Creative Commons / GE Healthcare / BD Biosciences / Shimizu / Women’s Hospital Inc / Macmillan Publishers Limited / /

Country

Germany / Belgium / France / United States / United Kingdom / Denmark / /

Currency

pence / /

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Event

Product Issues / /

Facility

Jefferson University / Flanders Institute / RIP1-RIP3 complex / Technical University of Denmark / Tufts University / Ph.D. University / Thomas Jefferson University / Ghent University / /

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IndustryTerm

active site / cellular systems / chemical inhibitors / software package / control / pocket-like active site / chemical identity / methyl / Animal protocols / Chemical inhibitor / restriction site / energy metabolism regulator / /

MedicalCondition

TNF-induced necrosis / murine disease / TB / experimental disease / severe sepsis / mouse experimental disease / injury / Because RIPK1 deficiency / septic shock / accelerated hypothermia / mediate retinal detachment-induced photoreceptor necrosis / sepsis / murine experimental disease / response syndrome / programmed necrosis / lipopolysaccharide-induced endotoxin shock / necrosis / cancer / lethal systemic inflammatory response syndrome / Disease / ischemic brain injury / shock / systemic inflammatory response syndrome / hypothermia / virus-induced inflammation / tumor necrosis / RIP kinase-dependent necrosis / tumor necrosis factor / infection / renal ischemia/reperfusion injury / deficiency / inflammation / TNF-induced shock / TNF-induced hypothermia / /

MedicalTreatment

chemotherapy / immunosuppression / induced hypothermia / /

NaturalFeature

L-1-MT / /

Organization

Jefferson University / Philadelphia / Harvard Medical School / Technical University of Denmark / TNF administration / Special Research Fund / Department of Pathology / Ghent University / Flemish Government / 4Lankenau Institute for Medical Research / Women’s Hospital / Nec-1 administration / Nec-1i administration / Tufts University / Boston / Department for Molecular Biomedical Research / School of Medicine / Thomas Jefferson University / Philadelphia / European Union / Department of Pathology / Anatomy / and Cell Biology / 6Kimmel Cancer Center / Flanders Institute / /

Person

Van de Craen / Van Hauwermeiren / Arch Biochem Biophys / Antonia S. Indoleamine / Amin Bredan / /

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Position

Walker / Butler / advanced semantic chemical editor / P-RIPK1 P-RIPK3 WB / professor / USA *Corresponding author / LeGolvan MP / /

Product

penicillin / M-60 / RIPK1 / EDTA-free Protease Inhibitor Cocktail Tablets / acetic acid / TNT / Jurkat cells / Jurkat cells / 9 / 10 / 36 / Jurkat cells.10 From / /

ProvinceOrState

Hawaii / /

PublishedMedium

PLoS One / /

Technology

alpha / molecular modeling / Biotechnology / cloning / apoptosis / chemotherapy / pharmacodynamics / /

URL

http /

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