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Immunology / Immune system / T cells / Glycoproteins / Applied genetics / CD25 / Autoimmunity / Intravenous immunoglobulin / FOXP3 / Biology / Medicine / Anatomy


Document Date: 2013-02-28 11:18:47


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City

Leiden / Philadelphia / Walker / Amsterdam / Tregitope / /

Company

Cousens LP / Proc Natl Acad Sci U S A / Yasayko SA / IgG / Cox / EpiVax Inc. / /

Country

Netherlands / United States / /

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Facility

Children’s Hospital of Philadelphia / Hospital of Philadelphia / University of Rhode Island / Services University of Health Services / /

IndustryTerm

Pompe Disease Therapy / antigen-processing pathways / therapy for Pompe disease / Treatment of diabetes / potential therapeutic applications / treatment of CRIM-negative Pompe disease / treatment of autoimmune and inflammatory diseases / therapy for Gaucher disease / /

MedicalCondition

complete deficiency GAA / multiple myeloma / Lysosomal Storage Disorders / infectious complications / CRIM-negative infantile Pompe disease / allergic airway disease / multiple sclerosis / disorder / Introduction Pompe disease / inflammatory diseases / OVA-antibody titer Enzyme Replacement Therapy Immune Tolerance Induction Influenza HA / lysosomal storage disorder / Hemophilia A / fulminant intestinal inflammation / Experimental model Finding Human disease / negative Pompe disease / chronic inflammatory demyelinating neuropathies / diabetes / Gaucher disease / antigen-specific Tregs Enzyme Replacement Therapy Immune Tolerance Induction Influenza HA / plasma cell leukemia / Fabry disease / deficiency / lethal hypersensitivity / systemic lupus erythematosus / inflammatory bowel disease / GAA deficiency / muscle inflammation / haemophilia / experimental autoimmune encephalomyelitis / chronic inflammatory demyelinating polyneuropathy / complete GAA deficiency / colitis / immune thrombocytopenic purpura / glycogen storage disease / Sjögren’s syndrome / MS / lupus / Pompe disease / enzyme deficiency / CRIM-negative Pompe disease / I Diabetes / autoimmune diseases / secondary immune thrombocytopenia / disease / certain infections / haemophilia B / congenital hemophilia / murine Pompe disease / inflammation / idiopathic thrombocytopenic purpura / human disease / Rituximab-associated infections / Treg Induction Allergy Anti-histamines / /

MedicalTreatment

immunoglobulin therapy / biologic therapies / enzyme replacement therapies / Insulin Therapy / gene therapy / enzyme replacement therapy / organ transplant / /

Organization

Tregitope administration / 5Uniformed Services University of Health Services / Institute for Immunology / Children’s Hospital of Philadelphia / Institute for Immunology and Informatics / University of Rhode Island / Administration of Tregitopes / 2Children’s Hospital of Philadelphia / Jordan SC / /

Person

Anne S. De Groot / W. Elyaman / Van Overtvelt / Ryan Tassone / Martinez Saguer / F. Mingozzi / Leslie P. Cousens / High / Gene Ther / /

Position

senior scientist / /

Product

Velcade / Rituxan / prednisolone / Copaxone / Campath / Tysabri / myozyme / /

ProvinceOrState

Rhode Island / /

PublishedMedium

PLoS One / /

RadioStation

Bilate AM / /

Technology

alpha / autoimmunity and inflammation / Immunotherapeutics / antibodies / transplantation / gene therapy / http / drug design / /

URL

http /

SocialTag