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Tumor markers / Tumor suppressor genes / BRCA mutation / Breast cancer / Lactams / PARP inhibitor / BRCA2 / Ovarian cancer / BRCA1 / Medicine / Oncology / Mutation


ARIEL2: A phase 2 study to prospectively identify ovarian cancer patients likely to respond to rucaparib Elizabeth Swisher,1 James Brenton,2 Scott Kaufmann,3 Amit Oza,4 Robert L. Coleman,5 David O’Malley,6 Gottfried Ko
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Document Date: 2014-11-25 16:41:42


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City

San Francisco / Rochester / Columbus / Seattle / Cambridge / Houston / Los Angeles / Toronto / Melbourne / /

Company

12Foundation Medicine Inc. / /

Country

Canada / Australia / United Kingdom / /

Facility

Research UK Cambridge Institute / Royal Melbourne Hospital / University of Texas MD Anderson Cancer Center / Ohio State University / University of Glasgow / James Cancer Center / University of Cambridge / Margaret Hospital / /

IndustryTerm

gene products / /

MedicalCondition

tumor BRCA / R Cell survival Cell death HRD=HR deficiency / ovarian cancer / measurable disease / Cancer / Identify High-Grade Ovarian Cancer Patient Tumors / endometrioid ovarian cancer / Adequate tumor / RECIST=Response Evaluation Criteria In Solid Tumors / deficiency / /

MedicalTreatment

chemotherapy / /

Organization

UCLA / 4Princess Margaret Hospital / 5The University / University of Cambridge / Ohio State University / James Cancer Center / Li Ka Shing Centre / 2Cancer Research UK Cambridge Institute / Washington School of Medicine / 8Rocky Mountain Cancer Center / 13The Royal Melbourne Hospital / University of Glasgow / Glasgow / University of Texas / /

Person

Elizabeth Swisher / /

ProvinceOrState

Texas / Ohio / Minnesota / California / Massachusetts / Washington / /

Technology

Pharmacokinetics / siRNA / chemotherapy / recombination / gene analysis / /

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