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Immunology / Antibody-dependent enhancement / Monoclonal antibodies / Dengue virus / Dengue fever / Human anti-mouse antibody / Hybridoma technology / Humanized antibody / Flavivirus / Biology / Medicine / Immune system


Development of a Humanized Antibody with High Therapeutic Potential against Dengue Virus Type 2 Pi-Chun Li1,2, Mei-Ying Liao2, Ping-Chang Cheng2, Jian-Jong Liang3, I-Ju Liu2, Chien-Yu Chiu2, Yi-Ling Lin3, Gwong-Jen J. Ch
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Document Date: 2014-10-02 03:12:04


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File Size: 2,31 MB

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City

Taipei / Chapel Hill / /

Company

Thermo Fisher Scientific / Sigma-Aldrich / Bio-Rad Laboratories / Merck / GE Healthcare / Mei / Jackson ImmunoResearch Laboratories / mAbs Isotype / IgG / Protein Data Bank / SignaGen Laboratories / INTEGRA Biosciences / GenBank / New England BioLabs Inc. / Biacore Inc / PCR / Macherey-Nagel GmbH & Co. KG. / Creative Commons / Specificity DB2 / /

Country

Taiwan / Malaysia / United States / /

Currency

pence / /

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Event

Extinction / /

Facility

National Defense Medical Center / Laboratory Animal Center National Taiwan University College of Medicine / C terminus / Institute of Biomedical / Institute of Biomedical Sciences / Institute of Cellular / University of North Carolina / Graduate Institute of Life Sciences / Fort Collins / /

IndustryTerm

block solution / control / mammalian expression systems / cDNA product / research tools / sensor chip / /

MedicalCondition

dengue fever / viral infection / heterologous virus infection / mild paralysis / severe life-threatening DHF/dengue shock syndrome / DENV2 infection / illness / Dengue Virus infection / DENV infection / paralysis / natural DENV infection / fever / primary DENV infections / days infection / virus infection / Dengue virus / dengue / infection / joint pain / Primary DENV infection / headache / Summary Dengue virus / important arthropod-borne viral disease / thrombocytopenia / infections / disease / antibody Introduction Dengue / sickness / dengue hemorrhagic fever / dengue infection / /

MedicalTreatment

immunotherapy / immunization / /

Organization

Committee on the Ethics of Animal Experiments of Academia Sinica / Institute of Cellular / National Defense Medical Center / Federal Communications Commission / National Taiwan University College of Medicine / National Laboratory Animal Center / Graduate Institute of Life Sciences / Institute of Cellular and Organismic Biology / University of North Carolina / Public Health Service / Institute of Biomedical / National Science Council / Centers for Disease Control and Prevention / Division of Vector-Borne Infectious Diseases / Institute of Biomedical Sciences / United States Department of Health and Human Services / /

Person

Duane J. Gubler / ELISA WB / /

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Position

original author / RT / Author / representative / Editor / WB / /

Product

TRIzol / DB32-6 / glycine / penicillin / amphotericin B / /

ProvinceOrState

Hawaii / Colorado / North Carolina / /

Region

West Nile / /

Technology

CM5 sensor chip / genotype / antibodies / directed mutagenesis / biopanning protocol / cloning / phage display / DNA sequencing / /

URL

www.plosntds.org / /

SocialTag