Brisson LC / International Prostate Screening Trial Evaluation Group / GE / Proc Natl Acad Sci U S A / Bernstein / Harmonisation E9 Expert Working Group / Pearson / / /
Facility
University of California Berkeley / A National Cancer Institute / National Institutes of Health Library / National Cancer Institute / University of Washington / National Institute of General Medical Sciences / Fred Hutchinson Cancer Research Center / /
IndustryTerm
specimencollection protocol / blood bank / biomarker-based screening tools / Early detection cancer research network / population-screening tool / diagnostic systems / diagnostic technologies / formal algorithms / well-defined and appropriate protocol / statistical algorithms / recent technology / statistical algorithm / /
MedicalCondition
ovarian cancer / JE / rare cancers / neuroblastoma / clinical disease / early-stage cancer / J Cancer / late-stage cancer / such cancers / cancer T / Study Results Tumor / such tumors / diverse disease / prostate cancer / MS / pancreatic cancer / specific screened cancer / cancers / tumor / cancer / tumors / disease / true disease / Human neoplasms / Early detection cancer / ovarian carcinomas / slow-growing cancers / colorectal and ovarian cancers / specific cancer / To monitor tumors / screen-detected tumors / preclinical disease / different cancer / /
MedicalTreatment
chemoprevention / surgery / /
Organization
National Cancer Institute / Department of Biostatistics / University of Washington / University of California / Department of Statistics / Public Health Service / National Institute of General Medical Sciences / Stat Assoc / Oxford University / Department of Health and Human Services / Fred Hutchinson Cancer Research Center / /
Person
Nicole Urban / Sandy Walbrek / Margaret Sullivan Pepe / Lian Schmidt / John D. Potter / Marcy Winget / Yutaka Yasui / Z. Feng / Gary Longton / Mark Thornquist / Ruth Etzioni / Nora Disis / Garnet Anderson / Mary Lou Thompson / /
Position
samples representative / messenger / representative of control subjects / Carter HB / representative / /
Technology
proteomics / Electrophoresis / antibodies / hybridization / screening protocol / statistical algorithm / specimencollection protocol / pharmacokinetics / cancer detection / laser / gene expression / spectroscopy / well-defined and appropriate protocol / simulation / drug development / /
COMMENTARY Phases of Biomarker Development for Early Detection of Cancer Margaret Sullivan Pepe, Ruth Etzioni, Ziding Feng, John D. Potter, Mary Lou Thompson, Mark Thornquist, Marcy Winget, Yutaka Yasui 1) INTRODUCTION