A Novel Method to Screen New Molecular Entities (NMEs) for Pharmacological Activity Against Cancer Summary: This invention proposes to screen new molecular entities in 2D cell cultures and 3D tissue models in the presenc

Source URL: kuic.ku.edu

• Cell culture
• In vivo
• Lung cancer
• Biology
• Biotechnology
• Cell biology

University of Kansas Innovation & Collaboration (KUIC) Proof of Concept (POC) Funding A. PROGRAM PRIORITIES The POC program is funded by the University of Kansas to further develop novel technologies that are near-commer

Source URL: kuic.dept.ku.edu

P.I.: KUIC_POC_Jan 2014 Kansas University Center for Technology Commercialization (KUCTC) Proof of Concept (POC) Fund Application

Source URL: kuic.dept.ku.edu

• Animal testing
• Institutional Animal Care and Use Committee
• Approval voting

Hyaluronic Acid Nanoparticles as Materials and Viscosity Modifiers Summary: The invention describes the application of nanoparticles made from hyaluronic acid to develop stable 3‐D colloidal gels and to enhance the rhe

Source URL: kuic.ku.edu

• Biology
• Science
• Glycosaminoglycans
• Hyaluronan
• Nanoparticle
• Tissue engineering
• Gel
• Biodegradable polymer
• Nanotechnology
• Chemistry
• Nanomaterials

Selective Small Molecule Activators of the Apoptotic Arm of the Unfolded Protein Response Summary: The invention involves the successful development of a first‐in‐class, potent, not generally cytotoxic, chemical pro

Source URL: kuic.ku.edu

• Immune system
• Proteins
• Cell signaling
• Apoptosis
• Unfolded protein response
• T cell
• Protein S
• Biology
• Cell biology
• Programmed cell death

Orally Dissolving Pullulan Capsules and Films Summary: This innovation has two forms: a hard capsule that dissolves orally and a film that dissolves orally. The capsules can be filled with a drug formulation containing a

Source URL: kuic.ku.edu

• Pharmacy
• Pharmaceutical industry
• Medicinal chemistry
• Capsule
• Tablet
• Excipient
• Pharmaceutical formulation
• Nutraceutical
• Bioavailability
• Pharmaceutical sciences
• Dosage forms
• Pharmacology

BRCA1-Based Breast or Ovarian Cancer Prevention Agents Summary: This invention is aimed at delaying the tumor growth in breast and ovarian cancers by increasing BRCA1 protein expression. Contact Information: Matt Koenig,

Source URL: kuic.ku.edu

• Tumor suppressor genes
• Breast cancer
• BRCA1
• Ovarian cancer
• Prostate cancer
• HER2/neu
• Cancer
• Hormonal therapy
• Management of cancer
• Medicine
• Oncology
• Ribbon symbolism

Signal-1/Signal-2 Bifunctional Peptide Inhibitors Summary: This invention provides a method of modulating T-cell pathways and subsequent immunity in a very spe -cific manner. Contact Information: Matt Koenig, J.D. KU Inn

Source URL: kuic.ku.edu

• Immune system
• Immunology
• T helper cell
• Antigen
• Major histocompatibility complex
• Autoimmunity
• Antigen presentation
• Co-stimulation
• Biology
• T cells
• Anatomy

KUIC Technology Profile Simplified Toll-like Receptor 2-Agonistic Monoacyl Lipopeptides Summary: The invention describes toll-like receptor 2-agonistic lipopeptides -propyl]-R-cysteinyl-S-serine (PAM2CS) compounds are po

Source URL: kuic.ku.edu

• Anatomy
• Toll-like receptors
• Immunologic adjuvant
• TLR 2
• Lipopeptide
• T helper cell
• ISCOM
• Immune system
• Immunology
• Biology

Novel Method for Digital Evaluation of Cellblocks Summary: Cervical cancer is one of the most common malignancies worldwide, yet it is clearly preventable by population screening. It has been reported that <5% of women i

Source URL: kuic.ku.edu

• Medical tests
• Vaccines
• Viral diseases
• Pap test
• Cervical cancer
• Human papillomavirus
• HPV vaccine
• Screening
• Papillomavirus
• Medicine
• Gynaecological cancer