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Mass spectrometry / Science / Proteins / Biotechnology / Bioinformatics / Quantitative proteomics / Stable isotope labeling by amino acids in cell culture / Chemical biology / Protein mass spectrometry / Biology / Chemistry / Proteomics


Discovery and validation of colonic tumor-associated proteins via metabolic labeling and stable isotopic dilution Edward L. Huttlina,1, Xiaodi Chenb, Gregory A. Barrett-Wiltc, Adrian D. Hegemand, Richard B. Halbergb,2, A
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Document Date: 2010-01-29 20:24:55


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City

St. Paul / Amsterdam / Boston / Atlanta / Spirulina / /

Company

Agilent Technologies Incorporated. / McClatchy / Applied Biosystems Inc. / Kline KG / bMcArdle Laboratory / Carr SA / Pearson / Gerber SA / Lucas AB / Venable / /

Country

United States / /

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Facility

University of Wisconsin-Madison Biotechnology Training Program / Stable Isotope Dilution / University of WisconsinMadison Institutional Clinical / University of Wisconsin-Madison Genome Sciences Training Program / University of Michigan / University of Wisconsin / University of Minnesota / Stable Isotopic Dilution Experiments / /

IndustryTerm

chemical labeling approaches / reagents/ analytic tools / food / solute carrier family protein / local alignment search tool / Cancer Prevention / dual-label microarray technology / biological systems / multidimensional protein identification technology / quantitative proteomic search / mRNA transcript processing / enriched food / /

MedicalCondition

JE / glioma cells / GDP dissociation / C olon cancer / mouse colon tumor / advanced intestinal cancers / esophageal cancer / breast cancer / muscle Heart Colon Lung Kidney Mammary gland Liver Small intestine Intestinal tumors / tumor / diffuse gliomas / cancer / tumors / neoplasm / used tumor / independent disease / Rho-GDP dissociation / colonic tumor / early lung cancer / endometriosis / each tumor RNA / prevalent cancer / endometrioid carcinoma / experimental colon cancer / colorectal tumors / adenomatous polyposis coli / human colon cancer / oral cancer / pressure-induced colon cancer / early Min tumors / colorectal cancer / †Tumors / human colonic adenocarcinomas / metastasis / colorectal cancers / familial adenomatous polyposis / spontaneous human colonic tumors / J Cancer / endometrial cancers / colon cancer / colonic tumors / MS / human breast cancer / cancers / breast cancers / adenomas / disease / intestinal tumors / gastrointestinal tumors / oral and esophageal cancer / hereditary colon cancer / Min tumor / human colonic tumors / human disease / /

MedicalTreatment

Head and Neck Surgery / /

MusicGroup

D.H. / /

NaturalFeature

Wang MT / /

Organization

University of Michigan / Department of Medicine / US Federal Reserve / American Cancer Society / cBiotechnology Center / Harvard Medical School / National Science Foundation / Department of Cell Biology / University of WisconsinMadison Institutional Clinical / Department of Oncology / University of Wisconsin / Madison / University of Minnesota / University of Wisconsin / /

Person

Michael A. Newtone / Gary Case / Adrian D. Hegemand / Amy C. Harmsc / Alexandra Shedlovsky / William F. Dove / Edward L. Huttlina / Linda Clipson / Barbara Michelson / Harlan Teklad / Michael R. Sussmana / Proc Natl Acad Sci / Gregory A. Barrett-Wiltc / William F. Doveb / Richard B. Halbergb / /

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Position

Washburn MP / reciprocal-labeling Author / /

ProgrammingLanguage

K / /

ProvinceOrState

Minnesota / Michigan / Nova Scotia / Wisconsin / Massachusetts / /

PublishedMedium

Cancer Research / Nature Chemical Biology / /

RadioStation

Bray AM / /

Technology

proteomics / cancer detection / DNA Chip / gene expression / genotype / Cellular Proteomics / Alpha / Electrophoresis / Biotechnology / transcriptomics / multidimensional protein identification technology / dual-label microarray technology / /

URL

www.pnas.org兾cgi兾doi兾10.1073兾pnas.0909282106 / http /

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