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Programmed cell death / Hypoxia-inducible factors / Immune system / Vascular endothelial growth factor / Autophagy / HIF1A / Apoptosis / Interferon / Biology / Cell biology / Transcription factors


Activation of HIF-1α (hypoxia inducible factor-1α) prevents dry eye-induced acinar cell death in the lacrimal gland
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Document Date: 2014-09-12 03:39:24

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File Size: 3,92 MB

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City

Ann Arbor / HIF / Santa Clara / Gyeonggi-do / Tokyo / Mountain View / San Jose / St. Louis / Santa Cruz / Minneapolis / Valencia / Boston / Seoul / Cambridge / Oberkochen / San Diego / Chicago / investigated using the HIF-1a CKO Figure / /

Company

Jackson Laboratory / McDermott / Agilent Technologies / Sigma-Aldrich / EPO / Qiagen / BD Biosciences / SPSS / Jackson Immunoresearch Laboratories / IgG / Nikon / Charles River Laboratory / COX / Creative Commons / Macmillan Publishers Limited / /

Country

Japan / Korea / United Kingdom / Germany / Sweden / United States / South Korea / /

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Facility

Hallym University College of Medicine / Bar Harbor / Hallym University Sacred Heart Hospital / Severance Hospital / Yonsei University College of Medicine / University of Ulsan College / Institute of Vision Research / Eye Research Institute / Laboratory Animals / Korea Health Industry Development Institute / /

IndustryTerm

mM solution / neural networks / hyaluronidase solution / imaging / Online Publication / radiological imaging / /

MedicalCondition

nonimmunological injuries / human breast carcinoma / JE / dysfunction / Sjo¨gren’s syndrome / starvation / injury / Breast Cancer / tumor / Hypoxia-induced tumor / cancer / non-Sjo¨gren’s syndrome / lacrimal gland inflammation / carcinogenesis / Sjogren’s syndrome-like disease / bone metastasis / Inflammatory / inflammatory signal / dry eye diseases / nonimmunologic injury / non-Sjo¨gren’s DE disease / inflammatory cell-infiltrated areas / Sjogren’s syndrome / inflammatory cytokines / inflammatory cells / MS / non-Sjogren’s disease / inflammatory cell infiltration / tumor necrosis factor-a / dry eye disease / Alzheimer’s disease / necrosis / glandular dysfunction / hypertension / hereditary paraganglioma / Disease / pheochromocytomas / Sjo¨gren’s DE disease / Hayashi T. Dysfunction / non-Sjogren’s syndrome / tumor necrosis / metabolic disease / inflammation / inflammatory cell invasion / /

Organization

Association for Research / Hallym University College of Medicine / Yonsei University College of Medicine / Definition and Classification Subcommittee of the International Dry Eye WorkShop / Korea Health Industry Development Institute / Clinical Trials Center / 2Schephens Eye Research Institute / Ministry of Education / Ministry of Health / Harvard Medical School / Severance Hospital / National Research Foundation of Korea / Institute of Vision Research / Department of Ophthalmology / Ulsan College of Medicine / Seodaemun-gu / Seoul / Korea and 6Institute of Corneal Dystrophy Research / Hallym University Sacred Heart Hospital / Animal Care and Use Committee / /

Person

Eun Ju Chang / Yuri Seo / Hyung Keun Lee / Changhun Park / Yong Woo Ji / Min Soo Park / Sang Mok Lee / Arch Ophthalmol / /

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Position

secretary / Author / representative / *Corresponding author / /

Product

Sigma / IL-1b / Nicotine / /

ProvinceOrState

South Dakota / Delaware / /

PublishedMedium

PLoS One / /

RadioStation

CKO / Curtis AM / /

Technology

Genotyping / stem cells / apoptosis / gene expression / 3g / alpha / antibodies / Biotechnology / condensation / /

URL

http /

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