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City Stockholm / La Jolla / L. A. / Cambridge / San Diego / Elowitz / / Company MIT Press / Hertz / AAAI Press / Armour / E. (2001) Genomic Regulatory Systems / / Country Sweden / United States / / / Facility ‡Stockholm Bioinformatic Center / Boston University / Fetzer Institute / New York University / University of California / Linko¨ping University / / Holiday Christmas / / IndustryTerm large-scale gene networks / controlled gene expression technologies / indirect information about network / cellular systems / systematic tools / cellular networks / reverse engineering algorithm / gene selection algorithm / protein network / synthetic gene networks / gene regulatory network / eukaryotic expression systems / large networks / gene network / chemical compounds / Reverse engineering gene networks / consistent solutions / possible input solutions / possible solutions / designer networks / segmentation polarity network / autoregulatory single-gene networks / given network / selection algorithm / microarray technology / systematic search / segmentation network / genetic network / overexpression technologies / genetic algorithms / gene regulatory networks / designer gene networks / input solutions / random network / denser networks / metabolic networks / particular network / search space / inconsistent solutions / numero gene network / consistent possible solutions / gene networks / / MedicalCondition diseases / / Organization Department of Biomedical Engineering / National Science Foundation / ‡Stockholm Bioinformatic Center / MIT / Stockholm Center for Physics / Astronomy / and Biotechnology / Department of Physics / University of California at San Diego / Swedish Research Council / Defense Advanced Research Planning Agency / Fetzer Institute / Center for BioDynamics / New York University / New York / Department of Bioengineering / Boston University / Boston / Wennergren Foundation / Division of Computational Biology / Royal Academy of Science / Linko¨ping University / / Person Jeff Hasty / Nat / K. Stephen Yeung / Tim Gardner / Jens Lagergren / James J. Collins / / Position designer / / ProgrammingLanguage EC / / ProvinceOrState New York / M. B. / California / Massachusetts / / PublishedMedium Molecular Biology / / Technology selection algorithm / Bioinformatics / Biotechnology / gene selection algorithm / metabolic networks / overexpression technologies / reverse engineering algorithm / DNA Chip / gene expression / microarray technology / how well controlled gene expression technologies / / URL www.pnas.org / www.pnas.org兾cgi兾doi兾10.1073兾pnas.0933416100 / / SocialTag 
Reverse engineering gene networks: Integrating genetic perturbations with dynamical modeling Jesper Tegne´r*†‡§, M. K. Stephen Yeung*, Jeff Hasty*¶, and James J. Collins* *Center for BioDynamics and Department of