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Epigenetics / RNA / Gene expression / Molecular biology / Transcription factor / Chromatin / Non-coding RNA / Green fluorescent protein / Biology / Genetics / Molecular genetics


LETTER Optical control of mammalian endogenous transcription and epigenetic states Silvana Konermann1,2*, Mark D. Brigham1,2,3*, Alexandro Trevino1,2, Patrick D. Hsu1,2,4, Matthias Heidenreich1,2, Le Cong1,2,5, Randall J
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Document Date: 2013-12-01 22:43:34

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Boston / Cambridge / Proudfoot / /

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United States / /

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Director’s Pioneer Award / /

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FDA Phase / Product Release / /

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C terminus / Zhang laboratory / McGovern Institute / Cambridge Center / N terminus / Massachusetts Institute of Technology / Broad Institute of MIT / Harvard University / /

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mRNA processing / injection site / online version / synthetic optogenetic transcription device / online paper / phototoxic products / exogenous chemical cofactors / versatile and robust technologies / optogenetic tools / repressor systems / target site / optic cannula implantation site / Online Content Any / dental cement / sonication device / /

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Harvard Medical School / National Institute of Health / Harvard University / Cambridge Center / MIT / Harvard / Massachusetts Institute of Technology / Broad Institute / MIT Committee on Animal Care / Institute for Brain Research / Department of Biological Engineering / Department of Brain and Cognitive Sciences / 2McGovern Institute for Brain Research / Department of Brain / /

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PublishedMedium

Molecular and Cellular Biology / Nature Protocols / /

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URL

www.nature.com/nature / www.nature.com/reprints / www.genome-engineering.org / /

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