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Guidelines for the welfare and use of animals in cancer research
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Document Date: 2014-07-27 23:36:17

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File Size: 1,41 MB

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City

San Francisco / Bradford / Manchester / Nottingham / Surrey / Southampton / Sausville / /

Company

Clare Hall Laboratories / 6OXiGENE Inc. / 10Tenovus Laboratory / 11Cancer Research Technology Development Laboratories / SR Wedge16 SA / Cancer Research UK British Journal / Wellcome Trust / Russell / AstraZeneca / mediators Limited / UK British Journal / /

Country

United Kingdom / United States / /

Currency

USD / /

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Facility

University of Manchester / Wolfson Institute / University of California San Francisco / Imperial College / General Hospital / Stopford Building / Hammersmith Hospital Campus / Laboratory Animal Welfare / Seacole Building / Institute of Cancer Research / University Hospital / 5Paterson Institute / University College London / USA Institute / Laboratory Animals / Charterhouse Square / Laboratory Animal Research / The National Cancer Research Institute / /

IndustryTerm

throughput technologies / experimental systems / Cancer Therapeutics / imaging / http /

MedicalCondition

colon adenomas / leukaemia / endocrine Additional loss / lymphoid tumours / xenograft response Experimental metastasis / ependymomas / medulloblastoma Rhabdomyosarcoma / clinical cancer / myeloid leukaemia Neural-crest-derived benign neurofibroma / skin cancer / fundamental cancer / neuroendocrine gastrointestinal tumours / Trp53 Osteosarcoma / Neuroblastoma / heptaocellular carcinoma / melanoma / U251 gliomas / M24met melanoma / pituitary Retinoblastoma / tuberous sclerosis / fibrosarcoma / lung adenocarcinoma / xenograft tumours / breast cancer / Brca1 Mammary tumours / hormonedependent tumours / glioblastoma / lymphoma / squamous-cell carcinoma Familial melanoma / Luciferase-expressing cancer / cancer / Uses cancer / NSCLC / Nf2 Osteosarcoma / growth kinetics Mimics late-stage ovarian cancer / p130 Retinoblastoma / adenocarcinoma PanIN NA Mutant Trp53 Pancreas-specific K-rasG12D+Ink4a/Arf deficiency / human cancer / malignant disease / hormone-responsive tumours / human cells Human cancer / sarcoma / thyroid carcinoma / carcinomatosis / PC3 prostate cancer / spontaneous metastasis / high-quality cancer / oesophageal carcinogenesis / Xenogeneic HCT116 colon cancer / infection / hamartomas / spontaneously arising tumours / peritoneal tumours / nude/SCID mice / short time frame B16 melanoma / inflammation/infection / K-rasG12D Lung adenoma / tumours / Rhabdomyosarcoma / common cancers / adenomatous polyposis coli / Nf2 Schwannomas / gastric cancer / tissue Metastases / Trp53 Mammary tumours / lymphoma / Subcutaneous tumours / germ-cell tumours / peritoneal mesothelioma / internal tumours / acute myeloid leukaemia / metastasis / transgenic tumours / breast Pancreatic adenoma / medulloblastoma Pancreatic adenoma / human cancers / allogeneic leukaemia models / Nf1 Pheochromocytoma / carcinoma / germ cell tumours Breast carcinoma / meningiomas / colon cancer / Cowden syndrome / Arf+/ mice Metastatic melanoma / mouse cancer / AR42J pancreatic carcinoma / urothelial tumours / osteosarcoma / medulloblastoma Additional loss / irradiated NOD/SCID / Intravenous 3DC13B lymphoma / mepatocellular carcinoma Schwannomas / gastrointestinaI tumour carcinomatosis / infectious agents / gastric cancer tumours / pancreatic cancer / ovarian carcinoma / mammary carcinoma / cancers / breast cancers / necrosis / chemically induced tumours / colon Mammary carcinoma / disease / models Advantages Disadvantages MC26 colon cancer / human situation 4T1 mammary carcinoma / real-time imaging Spontaneous tumours / Ink4a Fibrosarcoma / MLL fusion proteins AML AML MYCN Neuroblastoma / TUMOUR MODELS Preclinical cancer / tumour / Asymptomatic infection / lymphoma / soft-tissue sarcoma / A375 melanoma / Develop cancer / Table 2A Transplanted tumours / pain / squamous oesophageal carcinoma / high quality cancer / Intramuscular tumours / transgenic Ras-induced lung carcinoma / sarcomas / SCID / carcinomas / Inflammation / transplantable tumours / human disease / mammary carcinomas / /

MedicalTreatment

invasive procedure / Surgery / radiation / anticancer therapies / radiation therapy / chemoprevention / whole-body irradiation / gene therapy / /

Organization

2Comprehensive Cancer Imaging Centre / National Cancer Research Institute / UK’s National Centre for the Replacement / Refinement and Reduction of Animals / Southampton University School of Medicine / John Vane Science Centre / office of Laboratory Animal Welfare / London School of Medicine / Council on Accreditation / 5Paterson Institute for Cancer Research / Imperial College London Faculty of Medicine / University of Manchester / 4Helen Diller Family Comprehensive Cancer Center / Cancer Research UK Centre for Cancer Therapeutics / European Union / University of California San Francisco / 12National Centre for the Replacement / Institute of Cancer Research / University of Sheff / Department for Environment / Food and Rural Affairs / AAALAC’s Council on Accreditation / Natural Centre for the Replacement / Refinement and Reduction of Animals / USA Institute for Laboratory Animal Research / University College London / Simple administration / University Hospital / Natural Environment Research Council / Medical Research Council / Biotechnology and Biological Sciences Research Council / United Kingdom Coordinating Committee for Cancer Research / Wolfson Institute for Biomedical Research / General Hospital / London School of Medicine and Dentistry / Centre for Cancer & Inflammation / Queen’s Medical Centre / Advisory Committee on Genetic Modification / Advisory Committee on Dangerous Pathogens / /

Person

Blanche Lane / Peter Twentyman / Lloyd Kelland / John Vane / Correspondence / /

Position

Professor / Bishop / Workman / representative / Governor / Hunter / /

Product

Translational Therapeutics Kidney capsule / acetylcysteine / Bolus injection / A-07melanoma / Translational Therapeutics injection / testosterone / /

ProvinceOrState

California / North Carolina / /

PublishedMedium

Cancer Research / British Journal of Cancer / /

Technology

radiation / transfection/transgenic technology / stem cells / html / high-throughput technologies / biopharmaceuticals / gene expression / antibodies / Biotechnology / transplantation / gene therapy / /

URL

http /

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