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Signal transduction / Peripheral membrane proteins / Receptors / G protein-coupled receptor / Neurotransmitter receptor / Cell surface receptor / Heterotrimeric G protein / GTPase / Transducin / Biology / Membrane biology / Cell signaling


ARTICLE doi:[removed]nature10361 Crystal structure of the b2 adrenergic receptor–Gs protein complex
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Document Date: 2013-10-01 11:18:06


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Ann Arbor / Brussel / Copenhagen / J. Structure / Brussels / /

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Protein Data Bank / Macmillan Publishers Limited. / Parr Instrument Company / S.T.A.S. / Millipore / Qiagen / GE Healthcare / receptor-G / /

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Belgium / United States / Ireland / Denmark / /

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Event

Product Issues / /

Facility

terminus of Gas / Gs complex / Nb80 complex / Panum Institute / University of Copenhagen / terminus of GasRas / Nb35 complex / cAMP GTP / Trinity College / University of Michigan Medical School / University of Michigan / University of Michigan Biomedical Sciences Scholars Program / University of Wisconsin / /

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protease site / serum-free media / online version / precipitant solution / detergent solution / data processing / glycosylation site / centrifugal ultrafiltration device / protein solution / model-building tools / Experimental tools / crystallographic software / molecular replacement search / Structure solution / search models / dodecylmaltoside solution / /

Organization

UCLA / Sciences Institute / University of Michigan / Ann Arbor / Panum Institute / University of Michigan Medical School / Stanford University School of Medicine / Department of Biological Chemistry / University of Michigan Biomedical Sciences Scholars Program / Department of Molecular / Department of Molecular and Cellular Physiology / Science Foundation Ireland / Danish Council for Independent Research / Lundbeck Foundation / Mathers Foundation / RESEARCH ARTICLE Assembly of the b2AR / Trinity College / Dublin / Fund for Scientific Research of Flanders / General Services Administration / University of Wisconsin / Madison / 8Life Sciences Institute / University of Copenhagen / the University of Michigan / Stanford / /

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Fellowship / Van Eps / Tong Sun / Chen / V / K. Coot / /

Position

Author Information Coordinates / T.D. / Author / Junior Group Leader / model / /

Product

Gs / Viva / TNT / coupling / /

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Wisconsin / Michigan / California / /

PublishedMedium

Nature Protocols / /

Technology

Neuroscience / radiation / Protein engineering / X-ray / antibodies / cloning / cell signaling / human genome / ion exchange / drug discovery / phage display / structural genomics / protein sequencing / Crystallization / flash / /

URL

www.nature.com/nature / www.nature.com/reprints / /

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