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Systems biology / Molecular biology / Biotechnology / Protein-protein interaction assays / Interactome / Multiprotein complex / Proteomics / Protein–protein interaction / Immunoprecipitation / Biology / Biochemistry / Bioinformatics


Protein-protein interaction networks: probing disease mechanisms using model systems
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City

Santos / Toronto / /

Company

Integra / Proc Natl Acad Sci U S A / Bowie AG / Bajaj / Gillet LC / Hess / BioMed Central Ltd / Donnelly / Donaldson / Stephens / /

Country

Canada / /

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Facility

University of Toronto / College Street / /

IndustryTerm

protein interaction networks / action network / cellular systems / protein-protein interaction networks / protein products / phosphatase interaction network / basic technologies / physical interaction networks / higher eukaryotic model systems / cellular machinery / biological applications / yeast cell machinery / Recent applications / molecular machinery / therapeutics for a number of major diseases / informatics tools / certain biological systems / chromatin-remodeling machinery / assay systems / open-source software suite / human molecular network / protein interaction network / interaction networks / interactome sub network / basic model systems / model systems / cell systems / human protein-protein interaction network / human disease networks / action networks / /

MedicalCondition

adenomatous polyposis coli / muscular dystrophy / infectious context using recombinant viruses / Japanese encephalitis AP-MS / JE / HIV / common human disorders / neurodegenerative disease / Schizophrenia AP-MS / metastasis / Microbes HIV infection AP-MS / adenocarcinoma patient samples / MRSA infection AP-MS / microbial infections / congenital amaurosis / hepatitis C / cisplatin-treated squamous cell carcinoma / human melanoma / brain cancers / melanoma / hormone-responsive breast cancer / multiple sclerosis / par ticular disease / Lyme disease / aggres sive cancers / measles virus / MS / Normal state Disease state Homeostatic process Disease / Neisseria meningitides / breast cancer / common diseases / aggressive and indolent chronic lympho cytic leukemia / myopathies / lung tumor / cancers / specific diseases / tumor / insulin resistance / Alzheimer’s disease / Japanese encephalitis virus / cancer / Mouse Multiple sclerosis AP-MS / Pneumonia AP-MS / genetic and neurodegenerative disorders / schizophrenia / disease / p53/p63 master tumor / meningococcal diseases / HIV-host PPIs Viral infection AP-MS / human cancer / thereby preventing inflammation / infectious particle production / Japanese encephalitis / infectious particle composition / diabetes / cardiomyopathies / Lung cancer AP-MS / popular cervical cancer / Human Breast cancer AP-MS / p53 tumor / diseases / mad cow disease / cardiac disease / congenital amaurosis AP-MS / Measles AP-MS / infection / bovine spongiform encephalopathy / neurodegenerative diseases / Melanoma AP-MS / human disease / common p53 cancer / /

MedicalTreatment

chemotherapy / /

NaturalFeature

Criado MT / /

Organization

Banting and Best Department of Medical Research / Cornell / Medical Research and Donnelly Centre for Cellular and Biomolecular Research / University of Toronto / /

Person

Johnson JR / Uros Kuzmanov / Andrew Emili / Narayan V / Van Dijck / /

Position

Washburn MP / Biological General / model / representative / model for human inferences / /

Product

cisplatin / DS / /

ProgrammingLanguage

RC / /

ProvinceOrState

Mississippi / Ontario / be monitored using quantitative MS-based procedures / /

RadioStation

Michon AM / /

Technology

alpha / genomics / proteomics / Bioinformatics / basic technologies / antibodies / apoptosis / ion exchange / laser / drug discovery / gene expression / chemotherapy / glycomics / lipidomics / metabolomics / gel electrophoresis / /

URL

http /

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