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Anatomy / Lymphoma / Immune system / Monomethyl auristatin E / Monoclonal antibody therapy / Monoclonal antibodies / Antibody-drug conjugate / Ibritumomab tiuxetan / Anaplastic large-cell lymphoma / Medicine / Biology / Immunology


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City

Topsham / Washington DC / Camarillo / Bothell / Wilmington / Indianapolis / Milford / Milwaukee / Meriden / San Jose / /

Company

IgG / Fairchild / cAC10-vcMMAE / McMillan SA / Hawkins SA. / Agilent / Becton Dickinson / Seattle Genetics / Zellkulturen GmbH / Donaldson / CellQuest Software / /

Country

Germany / /

/

Event

FDA Phase / /

Facility

University of Texas Southwestern Medical Center / /

IndustryTerm

stock solution / clinical applications / atmospheric pressure chemical ionization source / sheath gas / cancer therapy / potential product / treatment of acute myeloid leukemia / tumor site / marine natural product / treatment of cancer / model systems / treatment of Hodgkin’s disease / drug-linker degradation products / drug-linker solution / ice-cold staining media / cold-reduced antibody solution / drug-linker stock solution / /

MedicalCondition

specific cancers / HD tumors / rheumatoid synovitis / HDLM2 Hodgkin disease / JE / lymphoma / lymphoma cell lines / Hodgkin’s disease / ALCL tumor / rituximab-refractory tumors / large granular lymphoma cell line / well-established tumors / multiple sclerosis / complete / durable tumor / anaplastic large cell lymphoma cell line Karpas / complete tumor / subcutaneous and disseminated tumor / severe disease / head tumors / MS / localized scleroderma / large colon tumor / Hodgkin disease / neck tumors / only slight tumor / chronic autoimmune / Leukemia / tumor / breast cancers / different tumor / immunologic diseases / cancer / tumors / disease / CD30-expressing hematologic malignancies / average tumor / L540cy Hodgkin disease cells / subcutaneous disease / Hematology Introduction The tumor necrosis factor / large granular lymphoma cell line YT / nM L540 Hodgkin disease / partial tumor / lymphomatoid papulosis / disseminated disease / epithelial tumors / human anaplastic large-cell lymphoma xenografts / L540cy tumors / anaplastic large cell lymphoma / non-Hodgkin lymphoma / antigen-positive tumor / SCID / L540cy HD tumor / lymphoma lines / acute myeloid leukemia / hindlimb paralysis / /

MedicalTreatment

chemotherapy / radioimmunotherapy / Immunotherapy / cancer therapy / antibody therapy / /

OperatingSystem

XP / /

Organization

University of Texas Southwestern Medical Center / Dallas / American Society of Hematology BLOOD / Society of Hematology / American Society / Animal Care and Use Committee / /

Person

Ron DeBlanc / Barth S. Recombinant / Harlan Bioproducts / Svetlana O. Doronina / Raji Burkitt / Damon L. Meyer / Che-Leung Law / Alan F. Wahl / Peter D. Senter / Bruce J. Mixan / Clay B. Siegall / Nick-Vincent Maloney / Younes A. Rituximab / Joseph A. Francisco / Dana F. Chace / Phil Thorpe / Kristine A. Gordon / Starr X. Rejniak / Charles G. Cerveny / Brian E. Toki / Kerry Klussman / Alan F. Wahl Updated / /

Position

King / representative / /

Product

DTPA / After injection / ES / mitomycin / Mylotarg / paclitaxel / dimethyl sulfoxide / Taxol / CD30 / CD33 / /

ProgrammingLanguage

DC / /

ProvinceOrState

YT / Washington / /

Technology

ADC / antibodies / polymerization / Apoptosis / drug delivery / DNA synthesis / chemotherapy / treating cancer / ADC technologies / targeted chemotherapy / /

URL

http /

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