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City Rotterdam / / Company Molecular Life Sciences REVIEW / M. L. C. / / Country Netherlands / / / Facility Sophia Children’s Hospital / University Medical Centre / / IndustryTerm information processing / treatment of the underlying disease / magnetic resonance imaging / treatment of underlying disease / energy / cognitive processing / energy level / treatment of fatigue in patients with neuromuscular disorders / neuronal processing / treatment for fatigue in other neuromuscular disorders / treatment of fatigue in neuromuscular disorders / ergo-therapeutic devices / Treatment of fatigue in neuromuscular disease / treatment of myasthenia gravis / revealed using magnetic resonance imaging / / MedicalCondition neuromuscular disorders CIS / hereditary polyneuropathy / brain and respiratory acidosis / VAS-F Pompe disease / MFI Post-poliomyelitis syndrome / hypertrophic cardiomyopathy / late-onset Pompe Fatigue / chronic variety / both experienced fatigue / acute and monophasic disease / MFI multidimensional fatigue / neurological disorders / pituitary diseases Intracranial infections / hypothalamic-pituitary diseases / dysfunction / twitch / neurological dysfunction / neuromuscular disease fatigue / chronic symptom / infectious illness / also other underlying diseases / cerebrovascular disease / neuromuscular disorders Neuromuscular disorders / wellknown chronic symptom / Pompe disease Pompe disease / Encephalitis Facioscapulohumural dystrophy / fatigue Neurological diseases / similar immune-mediated fatigue / mentioned neuromuscular disorders / experienced and physiological fatigue / multiple sclerosis / disorder / neuro-inflammatory diseases / metabolic disorders / tiredness / profound chronic fatigue / antecedent infections / CIDP / fatigue Guillain-Barre´ syndrome / myopathies / cerebral palsy / sleep-disordered breathing / physiological fatigue / neurological illness / hypoventilation / Granulomatous disorders / FSS fatigue / demonstrable muscle weakness / cancer / Severe fatigue / either psychiatric disease / myotonic dystrophy / pulmonary function / chronic fatigue syndrome / polyneuropathies / Chronic / physiological fatigue/residual nerve dysfunction / Respiratory dysfunction / lethargy / monophasic disorder / systemic diseases / viral infections / mental fatigue / FSS Myasthenia gravis / neuromuscular disorder / definitions Fatigue / post-poliomyelitis syndrome / chronic disease / Parkinson’s disease / encephalitis / muscle disease / diseases / Metabolic encephalopathy / Multiple sclerosis Multiple system atrophy Myotonic dystrophy Narcolepsy / hypotonia / infection / unidimensional fatigue / deficiency / generalized fatigue / limbic encephalitis / Sleep disorders / depression / mechanisms underlying fatigue / hand fatigue / somatic disease / CIS Fatigue / Peripheral fatigue / disorders / twitches / FIS fatigue / normal fatigue / neuromuscular disorders / overtrained athlete syndrome / autonomic dysfunction / local inflammatory process / cognitive symptoms / complete respiratory failure / obstructive sleep apnea / mostly progressive diseases / demonstrable somatic disease chronic fatigue / different neuromuscular disorders / Experienced fatigue Experienced fatigue / multidimensional fatigue / metabolic muscle disorder / neuromuscular diseases / chronic inflammatory demyelinating polyneuropathy / study addressing fatigue / Developmental disorders / muscle weakness / J. M. de Vries et al. disease / experienced fatigue / others neuromuscular diseases / fatigue / neuromuscular disease / glycogen storage disease / Springerlink.com Abstract Fatigue / muscle contraction / hypoesthesia / low-grade infections / Lyme disease / muscular atrophy / autosomal recessive disorder / residual fatigue / CIS Myotonic dystrophy / infections / motor neuron disease / Pompe disease / Post-infection fatigue / treatment Fatigue / PNS disease / myasthenia gravis / nocturnal hypoventilation / muscle atrophy / dissociation / rapidly progressive disease / Psychiatric diseases / Peripheral fatigue Central fatigue Central fatigue / systemic inflammatory response / metabolic myopathies Cerebral commotion Guillain-Barre´ syndrome / disease / Barre´ syndrome / often chronic diseases / Post-infectious fatigue / immune-mediated polyradiculoneuropathy / McArdle’s disease / pathophysiologic mechanisms causing fatigue / metabolic myopathies / Dysautonomia / contraction / neurological disease / how severe fatigue / poliomyelitis / inflammatory demyelinating polyneuropathy / pain / figure fatigue / immune-mediated polyneuropathies / acute post-infectious immune-mediated polyneuropathy / mitochondrial myopathies / acid maltase deficiency / chronic diseases / self-reported fatigue / respiratory insufficiency / neurological diseases / central fatigue / fatigue Cerebral vasculitis / meningitis / well-treated CIDP / CIS Charcot-Marie-Tooth disease / dysautonomia and psycho-sociological consequences / / MedicalTreatment cognitive therapy / surgery / exercise therapy / relaxation / mechanical ventilation / enzyme replacement therapy / cognitive behavioral therapy / / Organization World Health Organization / University Medical Centre / Sophia Children’s Hospital / The Netherlands J. B. J. Bussmann Department of Rehabilitation Medicine / Department of Neurology / Division of Metabolic Diseases and Genetics / Department of Paediatrics / / Person Molenwaterplein / / Position continuous feed forward / physician / Author / athlete / Governor / / Product modafinil / albuterol / / Technology magnetic resonance imaging / alpha / antibodies / / SocialTag 
Cell. Mol. Life Sci[removed]:701–713 DOI[removed]s00018[removed]Cellular and Molecular Life Sciences REVIEW