| Document Date: 2014-01-30 10:04:20
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City Wu¨rzburg / Friesoythe / Zwijnaarde / Heidelberg / Krefeld / Eppendorf / Nordenstadt / Erlangen / Wiesbaden / Frankfurt / / Company IgG / PAA Co / GraphPad Software / FAB633P / R&D Systems / FAB6302P / R&D Systems / scFv / BD Biosciences / CD70 / New England Biolabs GmbH / TNC / Macmillan Publishers Limited / / Country Germany / Egypt / United States / / Currency pence / / / Event FDA Phase / / Facility C terminus / mg/ml TRAIL / TRAIL Abbreviations / University Hospital Wu¨rzburg / Soluble TRAIL / Mansoura University / determined using the MTT assay Soluble TRAIL / / / IndustryTerm cancer therapy / human lambda light chain / region heavy chain / reduced processing / caspase processing / treatment of autoimmune diseases / / MedicalCondition B-cell lymphoma cell lines / multiple myeloma / chronic lymphocytic leukemia / mantle cell lymphoma / pancreatic tumors / solid tumors / clear cell renal cell carcinoma / colon cancer / melanoma / CD70-expressing solid tumors / B-cell lymphomas / renal cell carcinoma / squamous cell cancer / Cancer CD70 / glioblastoma / autoimmune diseases / cancers / tumor / cutaneous T-cell lymphoma / cancer / tumors / Disease / ADCC-mediated tumor / targeted tumor / diffuse large B-cell lymphoma / hematologic malignancies / tumor necrosis factor / non-Hodgkin lymphoma / CD70-secreting tumor / vaccinia / / MedicalTreatment cancer therapy / Immunostimulation / / Organization Division of Molecular Internal Medicine / Department of Biochemistry / Mansoura University / / Person Martin Gramatzki / Mino Jeko / / / Position RT / Ig leader / Belgium *Corresponding author / / Product General Electric E1035 Digital Camera / Fc / IL8 / / SportsEvent NHL / / Technology antibodies / cloning / apoptosis / phage display / treating cancer / http / / URL http /
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CD70-restricted specific activation of TRAILR1 or TRAILR2 using scFv-targeted TRAIL mutants