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City TGF / Boston / Mainz / NSCLC / / Company Eli Lilly / Novartis / Santaris Pharm A/S / Amgen / Incyte / Genentech / ITT / GlaxoSmithKline / Merck / Sanofi / Bristol-Myers Squibb / Aventis / Eli Lilly and Company / Polyphor Ag / Shionogi / Genzyme / Pfizer / Dupont / Teva / Schering-Plough / A2A / AstraZeneca / / Country Germany / United States / / Facility Israel Deaconess Medical Center / Johannes Gutenberg University / University Medical Center / / IndustryTerm cancer therapy / fibrosis imaging / chemokine systems / detoxification systems / oil vs. plac / / MedicalCondition experimental liver fibrosis / lower fibrosis / allergies / liver inflammation / primary sclerosing cholangitis / atopic dermatitis / HIV / multiple myeloma / HBV / special inflammatory environment / rheumatoid arthritis / clinical problem Fibrosis / plaque psoriasis / cirrhosis / hepatitis B / focal glomerulosclerosis / biliary and parenchymal liver fibrosis / renal fibrosis / chronic inflammation / non-small cell lung cancer / liver cirrhosis / Improved fibrosis / liver fibrosis Detlef Schuppan1 / lobular inflammation / asthma / focal segmental glomerulosclerosis / adult primary biliary cirrhosis / leukemia / Ishak fibrosis / Caroli’s disease / cancer / NSCLC / inflammatory lesion / eosinophilic esophagitis / idiopathic pulmonary fibrosis / hepatocellular carcinoma / carcinogenesis / endothelial dysfunction / portal fibrosis / liver diseases / human liver fibrosis / diabetes / Promedior Glaucoma / HCV / several rodent fibrosis / portal hypertension / gastric varices / advanced fibrosis / medulloblastoma / biliary diseases / infection / secondary biliary fibrosis / viral hepatitis / inflammatory / Fibrosis / chronic viral hepatitis B / uveitis / scar / C Improved inflammation / lymphoma / parasite infections / NR Improved fibrosis / spondylitis / significant fibrosis / radiation-induced cutaneous and subcutaneous fibrosis / hepatocellular cancer / CCL4induced liver fibrosis / No effect Decreased fibrosis / obesity / rapid fibrosis / inflammatory cells / retards fibrosis / inflammatory tissue destruction / chronic injury / MS / perisinusoidal fibrosis / psoriatic arthritis / sepsis / active biliary diseases / viral and alcoholic hepatitis / mild fibrosis / cancers / congenital hepatic fibrosis / faster liver fibrosis / severe post-transplant hepatitis C / insulin resistance / diabetic nephropathy / necrosis / interstitial kidney fibrosis / Disease / atherosclerosis / infant fibrosis / myeloid leukemia / extensive necrosis / biliary fibrosis / Crohn’s disease / advanced liver fibrosis / biliary atresia / tissue necrosis / viral cirrhosis / nephrotic syndrome / Liver fibrosis / ol Pending Cystic fibrosis / Mirage Cardiac fibrosis / experimental schistosomiasis / diabetes mellitus / allergic rhinitis / alcoholic hepatitis / non-biliary fibrosis / autoimmune hepatitis / inflammation / diet-induced obesity / chronic hepatitis B / / MedicalTreatment dietary supplement / AIH / radiation / cancer therapy / relaxation / antiretroviral therapy / counseling / Bariatric surgery / / Organization 2Beth Israel Deaconess Medical Center / Harvard Medical School / University Medical Center / Environmental Protection Agency / / Person Yong Ook / / / Position driver / downstream mediator / / Product Simvastatin / acetylcysteine / cyclosporine / glucagon / Omega / Losartan / Copaxone / Pentoxifylline / glycine / azathioprine / rosiglitazone / Pioglitazone / Irbesartan / folic acid / GS / Lamivudine / vitamin A / cyanocobalamin / adenosine / / ProvinceOrState Manitoba / Massachusetts / / PublishedMedium The Journal of Clinical Investigation / / SportsEvent NHL / / Technology radiation / siRNA / stem cells / apoptosis / gene expression / treating cancer / tomography / Biotechnology / transplantation / http / drug development / / URL http /
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Review series Evolving therapies for liver fibrosis Detlef Schuppan1,2 and Yong Ook Kim1 1Institute