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Integral membrane proteins / Cell communication / Channelopathy / Generalized epilepsy with febrile seizures plus / Sodium channel / Action potential / Membrane potential / Nav1.1 / Gating / Biology / Electrophysiology / Ion channels


10022 • The Journal of Neuroscience, November 3, 2004 • 24(44):10022–[removed]Neurobiology of Disease A Novel Epilepsy Mutation in the Sodium Channel SCN1A Identifies a Cytoplasmic Domain for ␤ Subunit Interaction
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Document Date: 2009-10-27 15:32:34


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City

Irvine / Piscataway / Hercules / Minneapolis / Valencia / Princeton / Cambridge / Cleveland / Foster City / Rockford / St. Louis / /

Company

M. H. Meisler3 / GenBank / Cummins / Qiagen / McCormick / Covance / Bio-Rad / Amersham Biosciences / /

Country

Italy / Japan / United Kingdom / /

Currency

pence / USD / /

/

Event

FDA Phase / Man-Made Disaster / /

Facility

University of Michigan Pharmacological Science Training Program / C terminus / University of Torino / University of Michigan / University of California / /

IndustryTerm

twopulse protocols / intermediate protocol / bp product / simulation software / ogous systems / ramp protocol / voltagedependent activation protocol / short protocol / external solution / slowvoltage ramp protocol / sample voltage protocol / step protocol / internal solution / constructed using the NEURON simulation software / /

NaturalFeature

Sodium channel / /

Organization

National Institute of Health / University of Michigan / Ann Arbor / University of Michigan Pharmacological Science Training Program / University of Michigan / University of California / Irvine / University of Torino / National Research Service / Department of Human Genetics / Society for Neuroscience / the University of Michigan / /

Person

Miriam H. Meisler / Complete Protease Inhibitors (Roche) / Maja Adamska / /

Position

HCC-100A Temperature Controller / General / tonic clonic General / representative / /

Product

lamotrigine / valproic acid / D1866Y / Nav1 / /

ProvinceOrState

Michigan / California / /

PublishedMedium

The Journal of Neuroscience / /

Technology

Neuroscience / step protocol / two-step protocol / antibodies / sample voltage protocol / separate voltagedependent activation protocol / intermediate protocol / cloning / long protocol / three two-pulse protocols / ramp protocol / three protocols / twopulse protocols / short protocol / slowvoltage ramp protocol / simulation / same protocol / gel electrophoresis / analyzed using a step protocol / tested using a slowvoltage ramp protocol / determined using three two-pulse protocols / determined using a two-step protocol / /

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