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City San Francisco / Cambridge / New Haven / / Company TRPA1 / Millipore / Sigma-Aldrich / N.J.H. L.C. / MA. Hydra Biosciences / Hydra Biosciences / bHydra Biosciences Inc. / TRPV1 / LG / Luminex / Charles River Laboratories / Phoenix Pharmaceuticals / Jackson Laboratories / C57 / M.F. L.C. / / Country United States / / / Event Product Issues / Natural Disaster / / Facility Laboratory Animal Care / University of California / National Institute of Environmental Health Sciences / Memorial Drive / Yale University / / IndustryTerm immune and nervous systems / carrier methyl cellulose / chemical and immunological stimuli modulating inflammation / endogenous reactive products / dose solutions / lipid peroxidation products / tear gas agents / noxious chemicals / mustard oil / reagents/analytic tools / chemical irritants / physiological systems / chemical exposures / / MedicalCondition inflammatory response / inflammatory thermal / mechanical hypersensitivity / local inflammation / Diisocyanate asthma / airway inflammation / mechanical hyperalgesia / inflammatory mediators / Th2-directed systemic inflammatory response / acute asthma / Pulmonary / allergen-induced airway inflammation / asthma Ana I. Caceresa / chemical and immunological stimuli modulating inflammation / inflammatory peptide release / respiratory diseases / Asthma / inflammatory pain / Th2-directed local inflammatory response / inflammatory action / acute and inflammatory pain / Allergy / allergic inflammatory response / reactive airway dysfunction syndrome / inflammatory leukocyte infiltration / local inflammatory responses / inflammatory cell densities / irritation / impaired acute and inflammatory neuropeptide release / impaired inflammatory response / inflammatory progression / bronchoconstriction / eosinophilia / inflammatory leukocytes / allergic airway inflammation / Flexivent pulmonary mechanics analyzer / inflammatory neuropeptide release / Airway eosinophilia / diminished eosinophilia / inflammatory pain sensitization / tissue inflammatory response / respiratory irritation / asthmatic airway inflammation / antigen-provoked cough / inflammatory cells / bronchial inflammatory diseases / MS / Decreased inflammatory response / allergic inflammatory conditions / disease / asthma epidemic / allergen-induced inflammatory leukocyte infiltration / reactive airways dysfunction syndrome / Chemosensory deficiency / inflammatory signaling pathways / pain / TRPA1 Antagonist Reduces Airway Inflammation / inflammatory disorder / chronic cough / moderate persistent asthma / cough / inflammation / neurogenic inflammation / inflammatory actions / allergic and occupational asthma / / MedicalTreatment Positive end-expiratory pressure / immunization / / MusicAlbum HC / / MusicGroup A.I. / / Organization American Asthma Foundation / University of California / German Research Foundation / PA PA / National Institute of Environmental Health Sciences / Scientific Advisory Board of Hydra Biosciences / Administration of HC-030031 / eLung Biology Center / PBS (PBS) / National Institute of Health / i.v. administration / Yale University School of Medicine / Spanish Ministry of Science and Innovation / Yale University / Association for Assessment and Accreditation of Laboratory Animal Care / / Person Sven-Eric Jordta / Occup Med / Ly Ma / Lauren Cohnd / Robert J. Homerc / Lesley Devine / David Julius / Aiwei Sui / Neil J. Haywardb / Maxwell D. Eliaa / Donato del Caminob / Bret F. Bessaca / Magdalene M. Moranb / Marian Brackmanna / Ana I. Caceresa / Lily Y. Jan / / Position major neuronal mediator / mediator / mice Author / / Product BAL / Sigma / IL-13 / IL-17 / Taqman / IL-5 / isoflurane / pancuronium / induction / C57/BL6 mice / acute and inflammatory neuropeptide release / mice / inflammatory response / / ProvinceOrState M.B. / Connecticut / M. B. / California / / PublishedMedium Critical Care Medicine / / RadioStation Roberts AM / Sci Am 294 / / Technology alpha / OVA protocol / antibodies / / URL www.pnas.org/cgi/content/full / www.pnas.org兾cgi兾doi兾10.1073兾pnas.0900591106 / / SocialTag 
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma Ana I. Caceresa, Marian Brackmanna, Maxwell D. Eliaa, Bret F. Bessaca, Donato del Caminob, Marc D’Amoursb, JoAnn S. Witekb,