assay protocol / concentrated toxoid solution / less stringent detoxification protocols / final product / receptor binding site / inactivation protocols / generated cleavage product / /
MedicalCondition
real infection / final tetanus / active tetanus / Tetanus neurotoxin / pertussis / severe spasms / Diphtheria / tetanus / poliomyelitis / veterinary tetanus / tetanus disease / formaldehyde-treated tetanus / severe muscle spasms / Germany Summary Tetanus neurotoxin / /
Movie
Conflict of interest / /
Organization
National Institute of Health / European Directorate for the Quality of Medicines and Healthcare / Animalfree Research Foundation / German Federal Ministry of Education / Medical School Hannover / Foundation for the Promotion of Alternate and Complementary Methods / Paul-Ehrlich-Institut / Beate Krämer Paul-Ehrlich-Institut / European Pharmacopoeia Commission / Federal Institute for Vaccines and Biomedicines / Council of Europe / Federal Ministry of Food / Agriculture and Consumer Protection / Doerenkamp-Zbinden Foundation / /
Person
Karin Duchow / Kay-Martin Hanschmann / Karin Weisser / Thomas Binz / Ursula Bonifas / Birgit Kegel / Beate Krämer / Katja Silberbach / Heike A. Behrensdorf-Nicol / Jolanta Klimek / Dev Biol / / /
Review Article “BINACLE” Assay for In Vitro Detection of Active Tetanus Neurotoxin in Toxoids Heike A. Behrensdorf-Nicol, Karin Weisser and Beate Krämer