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Cell cycle / DNA repair / Tumor suppressor genes / Ataxia telangiectasia mutated / Transcription factors / Nibrin / MRN complex / Ataxia telangiectasia / P53 / Biology / Cell biology / Proteins


REVIEWS ATM AND RELATED PROTEIN KINASES: SAFEGUARDING GENOME
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Document Date: 2003-04-07 17:25:52


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Company

Inez Myers Laboratory / /

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Event

Product Issues / /

Facility

Tel Aviv University / MDM2 complex / FA complex / MRN complex / S checkpoint / Abraham’s laboratory / /

IndustryTerm

cancer prevention / cellular systems / reactive chemicals / degradation systems / machinery / protein translation machinery / intricate signalling network / chemical nature / survival response machinery / spontaneous chemical changes / early damage processor / telomere-maintenance machinery / catalytic site / survival response network / intricate network / response systems / chemicals / /

MedicalCondition

deformities / genomic instability syndrome / Thompson syndrome / human disorder / squamous-cell carcinomas / severe mental retardation / facial erythema / Fanconi’s anemia / severe / progressive neuromotor dysfunction / deafness / A-T. This disorder / xeroderma pigmentosum / ataxia-telangiectasia-like disease / Cockayne’s syndrome / human diseases / breast cancer / Nijmegen breakage syndrome / cancers / genetic disorder ataxiatelangiectasia / mental retardation / ataxia-telangiectasia / cancer / genetic disease / disease / ATM deficiency / Bloom’s syndrome / human genetic disorder / mental deficiency / another genomic instability syndrome / rare disease / early cataracts / Cockayne’s syndrome This UV-light sensitivity syndrome / tumour / diabetes / dwarfism / sporadic solid tumours / A-T-like disease / diseases / deficiency / Werner’s syndrome / MRE11 deficiency / DSB signalling Ataxia telangiectasia / disorders / apparent cancer / /

MedicalTreatment

radiation / radiation treatment / /

OperatingSystem

XP / /

Organization

Department of Human Genetics and Molecular Medicine / Tel Aviv University / Tel Aviv / Sackler School of Medicine / /

Person

Yosef Shiloh / /

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Position

player / small head / /

Product

hydroxyurea / activation / DNAdamage response / phosphorylation / protein / BLM / response / responses / proteins / MRE11 show / /

Technology

radiation / ATM / early damage processor / apoptosis / DNA synthesis / gene expression / condensation / recombination / /

URL

www.nature.com/reviews/cancer / /

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