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City Edmonton / Montreal / Halifax / / Company Rai / nCR / w/ NCI / the AEs / / Country United States / Canada / / Currency pence / / Event FDA Phase / / Facility Queen Elizabeth II Health Sciences Centre / University of Alberta Hospital / Dalhousie University / Maisonneuve-Rosemont Hospital / / IndustryTerm healthcare / organ systems / body systems / chemical / Treatment of Unfit Patients with Chronic Lymphocytic Leukemia / / MarketIndex Charlson Comorbidity / / MedicalCondition glaucoma / kidney stone / lymphocytic leukemia / headaches / lymphoma / dementia / aneurysm / Fibromyalgia / chickenpox / bronchitis / dysfunction / Leukocytopenia / cerebrovascular accident / Nausea / gastroesophageal reflux / thrombocytopenia / hypercoagulability / Cerebrovascular disease / alopecia / important hearing impairment / hemiplegia / recurrent embolism / peripheral neuropathy / terminal heart failure / unstable angina / fatigue / deafness / obesity / myocardial infarct / pulmonary embolism / granulocytopenia / angina / severe liver disease / chronic pulmonary disease / end-stage renal disease / constipation / minor injuries / infections / Chronic Lymphocytic Leukemia David MacDonald / symptomatic angina / New Evidence Background Assessing patient fitness Chronic / sepsis / asthma / peripheral atherosclerotic disease / arrhythmia / leukemia / congestive heart failure / peripheral vascular disease / pneumonia / oxygen-dependent chronic obstructive pulmonary disease / almost complete blindness / hypertension / cancer / spontaneous pneumothorax / disease / ulcer disease / emphysema / Chronic / neutropenia / Vertigo / tumour / diabetes / severe renal disease / severe bronchospasm / vomiting / myocardial infarction / drug abuse / allergic rhinitis / osteoporosis / AIDS / infection / mild liver disease / dizziness / thrombosis / depression / rash / connective tissue disease / anemia / cataract / common leukemia / small lymphocytic lymphoma / / MedicalTreatment Chemo / appendectomy / carotid endarterectomy / vaccination / Chemotherapy / surgery / minor surgery / hysterectomy / bypass / major surgery / heart surgery / vascular surgery / lung surgery / dialysis / / MusicGroup Nausea / / Organization Health Sciences Centre / University of Alberta / Maisonneuve-Rosemont Hospital / American Society / Dalhousie University / / Person David MacDonald / Benjamin Fuerth / Loree Larratt / Silvy Lachance / / Position physician / Patient fitness types* Patient fitness General / Major / Medical Writer / Associate Professor / Professor of Medicine / / Product dexamethasone / cyclophosphamide / Pentostatin / prednisone / CLL4 / ML21445 / / ProvinceOrState Alberta / Quebec / Nova Scotia / / Technology Chemotherapy / dialysis / / SocialTag 
A Canadian Perspective on the Treatment of Unfit Patients with Chronic Lymphocytic Leukemia David MacDonald, MD, FRCP(C);* Silvy Lachance, MD, FRCP(C), CSPQ;† Loree Larratt, MD, FRCP(C)‡ *Dr. David MacDonald, Assista