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Cell biology / Congenital muscular dystrophy / Fukutin / Walker–Warburg syndrome / Dystroglycan / Laminin / Utrophin / Limb-girdle muscular dystrophy / Glycosylation / Muscular dystrophy / Biology / Health


Overview: Dystroglycan is a major component of the dystrophin-glycoprotein complex (DGC) acting as a transmembrane bridge across the sarcolemmal membrane. Dystroglycan binds to laminin (mediated by O-linked glycosylation
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Document Date: 2010-05-05 13:25:34

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Kano / Low / /

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Jackson Laboratory / PhD McColl-Lockwood Laboratory / Moore SA / Cox / Hp / Yuasa / Shimizu / Dovico SA / Suzuki / Lemmon / /

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pence / /

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Product Issues / /

Facility

Jackson Laboratory / Molecular Therapy National Institute of Neuroscience National Center / Cell Chemistry University of Heidelberg Germany _sstrahl@HIP.uni-heidelberg.de__ / Contact Prof. Dr. Sabine Strahl Heidelberg Institute of Plant Sciences Department / Neuroscience McGill University Montreal General Hospital / Muscular Dystrophy Research Cannon Research Center Carolinas Medical Center / Molecular Neuroscience Hammersmith Hospital Imperial College / University Graduate School / SUNY Upstate Medical University / /

IndustryTerm

muscle satellite cells / satellite cells expressing dystroglycan / satellite cell response / /

MedicalCondition

mild muscular dystrophy / muscular dystrophy / myodystrophy / eye abnormalities / hydrocephalus / DG deficiency / JE / brain disorders / strain / muscle weakness / CMD / tremor / injury / Walker-Warburg syndrome / distinct congenital muscular dystrophies / nerve injury / cardiomyopathy / disease / brain diseases / congenital progressive muscular dystrophy / fukutin deficiency / severe muscular dystrophy / limb girdle muscular dystrophy / Brain abnormalities / muscular dystrophies / FKRP-related muscular dystrophies / congenital muscular dystrophy / human disease / fibrosis / /

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bypass / /

Organization

SUNY Upstate Medical University Syracuse / Division of Molecular Brain Science Department of Internal Medicine/Department of Physiology / Muscular Dystrophy Research Cannon Research Center Carolinas Medical Center Charlotte / Yuko Miyagoe-Suzuki Department of Molecular Therapy National Institute / Department of Neuroscience and Physiology / Neuroscience National Center of Neurology and Psychiatry Tokyo / Neuroscience McGill University Montreal General Hospital Montreal / Kobe University Graduate School / Centre for Research / Sabine Strahl Heidelberg Institute of Plant Sciences Department / Cell Chemistry University of Heidelberg Germany _sstrahl@HIP.uni-heidelberg.de__ / /

Person

Hu H. Mech Dev / Tatsushi Toda / Huaiyu Hu / Thomas Krag / Qi Lu / Sabine Strahl / /

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Position

VP / Prime Minister / Harper HA / model for fukutin related protein associated muscular dystrophies / /

Product

SC / Evans blue / retinal transmission / neuronal migration defects / /

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Pennsylvania / /

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alpha / Neuroscience / antibodies / gene expression / /

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