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Immune system / Ipilimumab / PD-1 / Cancer vaccine / PD-L1 / Cancer immunotherapy / CTLA-4 / Melanoma / Immunotherapy / Medicine / Immunology / Biology


Priming phase Effector phase MHC
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Document Date: 2014-01-24 11:51:27


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File Size: 3,38 MB

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City

PD / /

Company

Checkpoint / AEs / The New England Journal / Dendreon Corporation / Merck / Genentech USA Inc. / Bristol-Myers Squibb / /

Country

United States / /

Event

FDA Phase / /

IndustryTerm

pharmaceutical development / hybridoma technology / cancer therapy / cancer therapies / treatment of NHL and chronic lymphocytic leukemia / concurrent / treatment of melanoma / printing / /

MedicalCondition

inflammatory response / ovarian cancer / multiple myeloma / lymphoma / colorectal cancer / chronic autoimmune inflammation / chronic lymphocytic leukemia / killed infectious agents / follicular lymphoma / dermatitis / advanced / metastatic solid tumors / Dranoff G. Cancer / metastatic solid tumors / solid tumors / therapeutic cancer / Advanced melanoma / small cell lung cancer / colitis / castrationresistant prostate cancer / melanoma / fatigue / Unresectable stage III/IV melanoma / pulmonary edema / non-small cell lung cancer / diarrhea / Relapsed/refractory hematologic malignancy Monotherapy NCT01358721 / renal cell carcinoma / metastatic / castration-resistant prostate cancer / Advanced/metastatic squamous cell non-small cell lung cancer / pruritus / tumor / III/IV malignant melanoma / Introduction Cancer / Unresectable melanoma / Cancer / tumors / disease / NSCLC / follicular lymphoma patients / hypothyroidism / T cell Dendritic cell Lymph node Cancer / hepatocellular carcinoma / metastatic renal cell carcinoma / advanced solid tumors / chronic viral hepatitis Monotherapy NCT01472081 / hematologic malignancies / MHC Tumor / advanced cancer / TCR MHC Tumor / Cancer I / renal cell carcinoma Monotherapy NCT01658878 / Response Evaluation Criteria In Solid Tumors / nonsmall cell lung cancer / rapid and deep tumor / positive breast cancer / stable disease / advanced / treatment-refractory solid tumors / infectious diseases / infection / measurable tumor / different cancer / rash / established cancer / Metastatic melanoma / /

MedicalTreatment

radiation therapy / immunotherapies / active immunotherapy / passive immunotherapy / vaccination / chemotherapy / Immunotherapy / cancer therapy / immunosuppression / passive immunotherapies / cancer therapies / active immunotherapies / /

Organization

World Health Organization / Annual Society of Hematology / American Society of Clinical Oncology / NS NS / FDA / /

Position

anti-CTLA4 therapy vs physician / /

Product

Carboplatin / Herceptin / cisplatin / Rituxan / paclitaxel / dacarbazine / CT-011 / NCT01295827 / NSCLC / NCT01454102 / CTLA-4 / BMS-936559 / MK-3475 / /

PublishedMedium

The New England Journal of Medicine / /

SportsEvent

NHL / /

Technology

radiation / cell receptors / antibodies / chemotherapy / treating cancer / drug development / /

SocialTag