Forsyth / Surrey / Helsinki / Glasgow / Calgary / London / /
Company
Eli Lilly / 4Oncolytics Biotech Inc. / Oncolytics Biotech Inc / Fibrosarcoma Eastern Cooperative Oncology Group / 2Cancer Research UK Targeted Therapy Laboratory / AEs / Plate AE / Pharsight Corporation Inc. / Suzuki / Chester Beatty Laboratories / Alteon Inc. / /
Country
Netherlands / United Kingdom / / /
Event
FDA Phase / /
Facility
National Cancer Institute of Canada / University Medical Centre Utrecht / Institute of Cancer Research / Beatson Oncology Centre / National Cancer Institute / Royal Marsden Hospital / /
IndustryTerm
Cancer Therapy / imaging / tumor site / Treatment of Cancer / therapy of metastatic cancer / in vivo model systems / /
MedicalCondition
JE / Bacterial- and viral-induced inflammation / metastatic disease / non-small-cell lung cancer / colorectal liver metastases / non-small cell lung cancer / diarrhea / esophageal cancer / advanced breast cancer / breast cancer / adenocarcinoma / Fatigue GGT / tumor / measurable disease / Cancer / nasopharyngeal carcinoma / tumors / subcutaneous tumors / neutropenia lasting / chills / KRAS mutant tumors / advanced solid tumors / Advanced Cancer Martijn P. Lolkema1 / neutropenia / fever / Anorexia Myalgia Alopecia Pruritus / vomiting / AE* Pyrexia Nausea Vomiting Diarrhoea Chills ALT / diseases / infection / increased ALT / total disease control rate / nasopharyngeal cancer / cancer using / headache / solid tumors / nausea / Tumor infection / fatigue / lung and pancreatic cancer / Japanese cancer / chronic congestive heart failure / extensive mediastinal disease / MS / Infections / sepsis / marked tumor / disease / Advanced Cancer Martijn P. Lolkema / murine malignant melanoma / massive myocarditis / advanced cancer / EBV infection / metastatic cancer / Mol Cancer / metastatic nasopharyngeal carcinoma / /
Centre for Cell and Molecular Biology / American Association for Cancer Research Published OnlineFirst / Systemic administration / 3The Beatson Oncology Centre / American Association for Cancer Research / NHS / National Cancer Institute of the United States / Institute of Cancer Research / UK Central Research Ethics Committee / European Organization for Research and Treatment of Cancer / Drug Development Unit / Royal Marsden Hospital / Intravenous administration / National Cancer Institute of Canada / AACR Publications Department / /
Person
Johann S. De-Bono / Ann Oncol / Martijn P. Lolkema / Van Den Wollenberg / Van Der Bilt / Kevin Harrington / Hendrik-Tobias Arkenau / / /
Published OnlineFirst November 24, 2010; DOI:[removed].CCR[removed]A Phase I Study of the Combination of Intravenous Reovirus Type 3 Dearing and Gemcitabine in Patients with Advanced Cancer Martijn P. Lolkema, H