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Melanoma / Methadone / Anakinra / Chemistry / Organic chemistry / Drug rehabilitation


 Glucose-6-Phosphate Dehydrogenase Deficiency: Closely monitor for hemolytic anemia. (5.6)  Embryofetal Toxicity: Can cause fetal harm. Advise females of reproductive potential of potential risk to a fetus. TAFIN
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Document Date: 2013-06-04 11:53:48

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City

Reference / /

Company

GlaxoSmithKline / /

Event

FDA Phase / /

Facility

Laboratory Abnormalities Increased / /

IndustryTerm

healthcare / treatment of patients with unresectable or metastatic melanoma / administration site / /

MedicalCondition

photophobia / severe hyperglycemia / palmar-plantar erythrodysesthesia syndrome / headache / NA Alopecia Palmar-plantar / phosphate dehydrogenase deficiency / cysts / Myalgia Neoplasms / infestations Nasopharyngitis / alopecia / BRAF Wild-Type Melanoma / wild-type BRAF melanoma / ventricular septal defects / melanoma / fatigue / primary malignant melanoma / Interstitial nephritis / Iritis / Hypersensitivity / Headache General disorders / papilloma / constipation / Back pain / complicated fever / hypotension / Cough Infections / mediastinal disorders / tumor / hemolytic anemia / keratoacanthomas / squamous cell carcinoma / disease / arthralgia / pre existing diabetes / chills / cutaneous squamous cell carcinoma / Carcinogenesis / Hypophosphatemia / Hyperglycemia / cutaneous squamous cell carcinomas / diabetes / TAFINLAR Drug hypotension / fever / G6PD deficiency / Includes skin papilloma / phosphatase Hyponatremia / Pancreatitis / keratoacanthoma / eye pain / rigors / Dehydrogenase Deficiency / pre-existing diabetes / infection / BRAF V600E mutation-positive melanoma / deficiency / renal failure / rash / primary malignant melanomas / syndrome / Serious Febrile Drug Reactions Hyperglycemia Uveitis / metastatic melanoma / Uveitis / dehydration / /

MedicalTreatment

chemotherapy / contraception / /

Organization

Concurrent administration / DOSAGE AND ADMINISTRATION / FDA / /

/

Position

Headache General / /

Product

dexamethasone / carbamazepine / gemfibrozil / clarithromycin / rifampin / phenytoin / TAFINLAR capsule / ketoconazole / dacarbazine / V600 / V600E / TAFINLAR / /

Technology

UDP / Pharmacokinetics / chemotherapy / /

URL

www.fda.gov/medwatch / http /

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