P-glycoprotein

Results: 77



#Item
51Digoxin / P-glycoprotein / Pharmaceutical sciences / Pharmacology / IC50 / Pharmacodynamics

Lei Zang: Transporter DDI Evaluation in New Drug Application Submissions

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Source URL: www.fda.gov

Language: English
52Molecular biology / ABC transporters / Biology / P-glycoprotein

Advisory Committee Mtgs. Sample PPT

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Source URL: www.fda.gov

Language: English
53ABC transporters / Clinical research / Pharmaceutical industry / Pharmacokinetics / ATP-binding cassette transporter / P-glycoprotein / Ritonavir / Cytochrome P450 / CYP3A4 / Pharmaceutical sciences / Pharmacology / Chemistry

Subscriber access provided by FDA LIBRARY Article Scientific Perspectives on Drug Transporters and Their Role in Drug Interactions

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Source URL: www.fda.gov

Language: English
54Digoxin / ABC transporters / Torsades de pointes / Antiarrhythmic agent / Amiodarone / IC50 / Dabigatran / P-glycoprotein / Chemistry / Organic chemistry / Cardenolides

The Role of Drug Transporters in Drug Safety-Perspective from the FDA

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Source URL: www.fda.gov

Language: English
55ABC transporters / Aromatase inhibitors / Alkenes / AstraZeneca / Tamoxifen / Caco-2 / P-glycoprotein / Breast cancer / Medicine / Pharmacology / Biology

Questions for the Advisory Committee members- October 18, 2006

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Source URL: www.fda.gov

Language: English - Date: 2006-09-27 14:22:12
56Science / ABC transporters / Pharmaceutical sciences / P-glycoprotein / Drug discovery / Quantitative structure–activity relationship / Drug design / Enzyme inhibitor / Chemistry / Medicinal chemistry / Pharmacology

P-gp Specificity Prediction Module ACD/Percepta Overview P-glycoprotein (P-gp) is a clinically relevant efflux transporter that extrudes compounds from a large variety of cells. In most cases, potential drugs that are su

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Source URL: www.acdlabs.com

Language: English - Date: 2012-05-17 08:28:16
57Neurology / Pharmacokinetics / Animal physiology / Blood–brain barrier / Zoology / Partition coefficient / Permeation / P-glycoprotein / Brain / Biology / Chemistry / Medicinal chemistry

Blood-Brain Barrier Permeation Prediction Module ACD/Percepta Overview The ACD/Labs Blood Brain Barrier (BBB) Penetration module predicts if a given compound is permeable enough to exhibit activity in the CNS. This modul

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Source URL: www.acdlabs.com

Language: English - Date: 2012-05-17 08:07:24
58Cancer treatments / Ribbon symbolism / Multiple drug resistance / Chemotherapy / P-glycoprotein / Leukemia / Breast cancer / Drug resistance / Management of cancer / Medicine / Oncology / Pharmacology

CBA Pharma Homepage    

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Source URL: www.fda.gov

Language: English
59Chemistry / Pharmacokinetics / Clinical research / Pharmaceutical industry / ADME / P-glycoprotein / ATP-binding cassette transporter / Bioavailability / Drug discovery / Pharmaceutical sciences / Pharmacology / Medicinal chemistry

j613 Index 2/4/A1 cell 137 a

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Source URL: media.wiley.com

Language: English - Date: 2013-08-23 10:16:26
60P-glycoprotein / Cell membrane / Blood–brain barrier / Transporter associated with antigen processing / Discovery and development of tubulin inhibitors / ABC transporters / Biology / ATP-binding cassette transporter

P-Glycoprotein Overview The P-glycoprotein multidrug transporter (Pgp, ABCB1) is a member of the ABC (ATP-binding cassette) superfamily. This protein can export an astonishing variety of amphipathic drugs, natural produc

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Source URL: www.fluorosome.com

Language: English - Date: 2010-01-08 17:34:52
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