REVIEWS A G U I D E T O D R U G D I S C O V E RY Validating therapeutic targets through human genetics Robert M. Plenge1,2, Edward M. Scolnick2,3 and David Altshuler2,4,5

Source URL: www.plengegen.com

• Biomarker
• Penetrance
• PCSK9
• Cystic fibrosis
• Low-density lipoprotein
• Rheumatoid arthritis
• Genome-wide association study
• Statin
• Introduction to genetics
• Biology
• Genetics
• Familial hypercholesterolemia

Corporate Overview September 2014 Alnylam Forward Looking Statements This presentation contains forward-looking statements, within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securiti

Source URL: www.alnylam.com

• RNA interference
• Transthyretin
• Gene expression
• Small interfering RNA
• PCSK9
• Amyloidosis
• Biology
• Genetics
• RNA

Familial hypercholesterolaemia ACCE review

Source URL: www.genomics.health.wa.gov.au

• Apolipoproteins
• Cardiology
• Familial hypercholesterolemia
• Genetics
• LDL receptor
• Apolipoprotein B
• Nutrition
• Low-density lipoprotein
• PCSK9
• Biology
• Medicine
• Health

Alnylam Pharmaceuticals R&D Day December 12, 2014 Alnylam Forward Looking Statements This presentation contains forward-looking statements, within the meaning of Section 27A

Source URL: www.alnylam.com

• RNA interference
• Molecular genetics
• Small interfering RNA
• PCSK9
• Low-density lipoprotein
• Amyotrophic lateral sclerosis
• Genetics
• Biology
• RNA

January 9, 2015 Regeneron and Sanofi Announce Positive Topline Results from First Phase 3 Trials Evaluating Monthly Dosing of Alirocumab in Patients with Hypercholesterolemia Primary efficacy endpoints met in two trials

Source URL: files.shareholder.com

• Health
• Regeneron
• Low-density lipoprotein
• Pharmaceutical industry
• Statin
• PCSK9
• Clinical trial
• Pharmaceutical sciences
• Pharmacology
• Science

Primary Care Specialists releases 1st Newsletter

Source URL: www.medfusion.net

• Immune system
• Immunology
• Clinical research
• Pharmacology
• Low-density lipoprotein
• Allergen
• Allergy
• Onychomycosis
• PCSK9
• Medicine
• Health
• Allergology

Liphorus Pharmaceuticals announces financing of $6.4 million to support development of small molecules inhibitors targeting PCSK9 for the treatment of hypercholesterolemia MONTREAL, November 6, 2014 — Sanderling and Un

Source URL: www.sanderling.com

NEWS RELEASE For release on November 6, 2014 at 6 a.m. ET Creation of Liphorus Pharmaceuticals A significant investment in healthcare in Montréal based on research conducted at the IRCM

Source URL: www.sanderling.com

• Infrared countermeasure
• Infrared imaging
• École Polytechnique de Montréal
• HEC Montréal
• Medical research
• Sanderling
• PCSK9
• Michel Chrétien
• Université de Montréal
• Quebec
• Health

Could a protein be linked to Heart Attacks? OTTAWA, September 3, 2014 – A team of researchers at the University of Ottawa Heart Institute, led by Dr. Alexandre Stewart, have uncovered an intriguing link between heart a

Source URL: ottawaheart.ca

• Biology
• Cardiology
• Lipoproteins
• Statin
• Low-density lipoprotein
• Cholesterol
• PCSK9
• University of Ottawa Heart Institute
• Cardiovascular disease
• Health
• Medicine
• Aging-associated diseases

Could a protein be linked to Heart Attacks? OTTAWA, September 3, 2014 – A team of researchers at the University of Ottawa Heart Institute, led by Dr. Alexandre Stewart, have uncovered an intriguing link between heart a

Source URL: www.ottawaheart.ca

• Biology
• Cardiology
• Lipoproteins
• Statin
• Low-density lipoprotein
• Cholesterol
• PCSK9
• University of Ottawa Heart Institute
• Cardiovascular disease
• Health
• Medicine
• Aging-associated diseases