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Viruses / Tropical diseases / Animal diseases / Sexually transmitted diseases and infections / Lentiviruses / Rhesus macaque / HIV / Influenza / Yellow fever / Medicine / Biology / Microbiology


Pathophysiologic and Transcriptomic Analyses of Viscerotropic Yellow Fever in a Rhesus Macaque Model Flora Engelmann1, Laurence Josset2, Thomas Girke3, Byung Park4, Alex Barron5, Jesse Dewane6, Erika Hammarlund7, Anne Le
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Document Date: 2014-11-14 18:13:50

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File Size: 2,77 MB

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City

YFV / Bron / Brea / Riverside / Waterbury / Portland / Lyon / San Jose / Galveston / Union City / Billerica / San Diego / upregulated following YFV-17D infection / upregulated following YFV-DakH1279 infection / observed following YFV-17D infection / upregulated following YFV-17D / /

Company

Millipore Corporation / Diagnostic Insturments Inc. / Qiagen / Sanofi / NuGEN Technologies / IgG / Najı / Abaxis / Affymetrix / Beckman Coulter / Creative Commons / /

Continent

Africa / South America / /

Country

Senegal / France / Brazil / United States / /

Currency

USD / /

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Facility

Laboratory Animal CareInternational / Gene Therapy Institute / University of California Riverside / World Reference Center / Science University / University of Texas Medical Branch / National Institute of Health / Oregon National Primate Research Center / Plant Sciences / Laboratory Animals / /

IndustryTerm

hybridization solution / Image processing / metal ion binding activity / regulation z-score algorithm / /

MedicalCondition

mid-zonal necrosis / high systemic levels Infection / yellow fever virus / viral infection / HIV / Wild type yellow fever virus / yellow fever / lethal viral encephalitis / virus-induced lymphopenia / lymphopenia / animal developed viscerotropic disease / viscerotropic disease / thymoma / viral hemorrhagic disease / infectious dose / Peak viremia / Abstract Infection / measurable disease / Histological examination PLOS Neglected Tropical Diseases / yellow fever disease / infectious virus / profound viscerotropic disease / Rhesus Macaque Model PLOS Neglected Tropical Diseases / Introduction Yellow fever virus / wild type YFV-DakH1279 infection / thymus disorders / significant GC necrosis / infectious unit / kidney injury / fever / YF disease / viremia / significant injury / kidney failure / liver PLOS Neglected Tropical Diseases / infectious virus titer / DakH1279 infection / human viscerotropic disease / lethal YFV infection / AIDS / infection / epithelial tubular necrosis / Extensive hepatocytes necrosis / inflammatory responses / neurotropic disease / infectious units / lethal infection / significant liver injury / strain / LIMMA PLOS Neglected Tropical Diseases / nausea / severe lymphopenia / mild disease / prevalent hemorrhagic fever viruses / direct viral infection / profound lymphopenia / infectious units/animal / only shared process PLOS Neglected Tropical Diseases / Summary Yellow fever / infections / GC necrosis / malignant neoplasms / WT-YFV infection / myasthenia gravis / hypotension / necrosis / fatal yellow fever / lethal disease / cardiovascular shock / disease / Kidney dysfunction / hypothermia / infectious units/mL / liver injury / severe viscerotropic disease / PLOS Neglected Tropical Diseases / Discussion Yellow fever virus / non-fatal yellow fever disease / identified following infection / /

MedicalTreatment

antibiotics / organ transplant / /

Organization

World Reference Center for Emerging Viruses and Arboviruses / University of Texas Medical Branch / Gene Therapy Institute / Institutional Animal Care and Use Committee / Division of Neuroscience / School of Medicine / University of California Riverside / United States Department of Agriculture / Centre de Biologie / National Institute of Health / American Veterinary Medical Association / Division of Comparative Medicine / office of Animal Welfare / Oregon National Primate Research Center / Division of Biomedical Sciences / EH / Division of Pathobiology and Immunology / Preventive Medicine / Oregon Health and Science University / Portland / Department of Botany and Plant Sciences / Oregon Health and Science University / Portland / /

Person

AGA CGA CTG TGT GGT / Thomas Geisbert / Gene Ontology / AGA CTG AAG / Bauer / Ian Amanna / Robert Tesh / /

Position

original author / following forward / Author / representative / Editor / councilman / Fisher / /

Product

B6 / R2 / sodium pentobarbital / /

ProvinceOrState

California / Oregon / /

Technology

Neuroscience / Rhesus chip / apoptosis / IPA regulation z-score algorithm / DNA Chip / gene expression / CAT / antibodies / hybridization / Image processing / ATG / Gene Therapy / laser / /

URL

http /

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