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PRKAR1A / Signal transduction / Carney complex / Neurofibroma / Carcinogenesis / Neurofibromin 1 / Multiple endocrine neoplasia / LNCaP / P21 / Medicine / Biology / Oncology


Priority Report A Mouse Model for the Carney Complex Tumor Syndrome Develops Neoplasia in Cyclic AMP–Responsive Tissues 1,2
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Document Date: 2008-07-21 09:49:09

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Vector Laboratories / Proc Natl Acad Sci U S A / Cache River Press / Perkin-Elmer Life Sciences Inc. / BD Biosciences / Kuznetsov SA / AMP / The Jackson Laboratory / Spiegel / Dupont / Cox / Garrett / /

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pence / /

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Bar Harbor / Ohio State University / Carney complex / National Institute of Child Health / Nathans Institute / Minnesota Abstract Carney complex / National Cancer Institute / Mayo Clinic / Laboratory Medicine / National Library of Medicine / The Ohio State University / Johns Hopkins University / /

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Online Mendelian Inheritance / loxP site / animal protocols / tissue culture systems / /

MedicalCondition

neoplasms / JE / myxomas / human tumor / endocrine tumors / Mesenteric carcinoma / Carney Complex Other tumors / exhibited multifocal tumors / McCune-Albright syndrome / thymoma / pancreatic adenocarcinoma / Tumor / Pancreatic tumor / adenoma / Cancer / Cardiomyopathy / fibrosarcomas / tumors / histologically similar paw tumor / endocrine neoplasia syndrome / bilateral tumors / thyroid tumors / follicular adenoma / lymphomas / neurofibromatosis / mouse models involving schwannomas / Visible solid tumors / bronchioloalveolar carcinoma / pit adenoma / solid-pattern thyroid carcinoma / thyroid carcinoma / TEC3;Prkar1a loxP/loxP tumors / autosomal dominant neoplasia syndrome / nerve sheath tumors / pituitary tumors / disorders / tumours / primary pigmented nodular adrenocortical disease / externally obvious tumors / hyperplasia Carcinoma / thyroid carcinomas / case sterility / lymphoproliferative disease / thyroid neoplasms / carcinoma / gonadal tumors / neurofibromas / leukemias / inflammatory cells / same clinical syndrome / Carcinoma Carcinoma Lymphoproliferative disease Bronchioloalveolar carcinoma / schwannoma / epithelial thyroid cancer / cancers / neurofibromatosis type 1 / hemangiosarcomas / disease / tumor development / Fibrous dysplasia of bone / tail tumors / typical schwannomas / bone tumors / schwannomas / sarcomas / schwannoma formation / carcinomas / soft-tissue sarcomas / thyroid cancer / adrenal tumors / pituitary chromophobe adenoma / schwannoma samples / /

MedicalTreatment

chemotherapy / /

Organization

Department of Internal Medicine / I2005 American Association for Cancer Research / Institutional Laboratory Animal Care and Use Committee / General Services Administration / National Institute of Health / Johns Hopkins University / The Ohio State University / Columbus / National Institute of Child Health and Human Development / /

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Ludmila Matyakhina / Lawrence S. Kirschner / Robey P. Fibrous / Mayo Clin Proc / Graham Kay / Ian Tonks / Alex Grinberg / Kurt Griffin / Constantine A. Stratakis / Sara Lenherr / Heiner Westphal / Donna F. Kusewitt / Andrea P. Effects / William H. Towns II / Gordon H. Dominant / Ann N Y Acad Sci / /

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Miner / Fisher LW / Fisher / /

Product

adenosine / /

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ABC / /

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Ohio / California / New Jersey / Maryland / South Dakota / North Carolina / Massachusetts / /

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Cancer Research / Endocrinology / /

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X-ray / genotyping / stem cells / chemotherapy / gene targeting / genotype / recombination / 3G / antibodies / hybridization / Biotechnology / transplantation / cell manipulation / /

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