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Signal transduction / Membrane biology / Cell signaling / G protein coupled receptors / Agonist / Receptor / Ligand / Adrenergic receptor / Partial agonist / Biology / Cell biology / Pharmacology


© 2006 Nature Publishing Group http://www.nature.com/naturechemicalbiology LETTERS Coupling ligand structure to specific conformational switches in the b2-adrenoceptor
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Document Date: 2009-12-04 19:10:52


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Portland / Bradford / Palo Alto / /

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Hubbell / Steraloids Inc. / E Q L L S D N T SA C / Avatar Software / Green S.A. / Jobin Yvon Inc. / Amersham / Ligand / Bio-Rad / Wavelength (nm) SA / /

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United States / /

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University of Washington / Campus Drive / Science University / /

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energy costs / beta2 adrenoceptor binding site / fluorescence resonance energy transfer / chemical groups / binder site / /

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University of Washington / Biomolecular Structure Center / Mather’s Charitable Foundation / Molecular Biology / Oregon Health & Science University / S.B. A / Stanford University School of Medicine / Stanford / /

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HAL C HO / HAL CH HO / Nat / AL P HO CH ICI / Bacon / /

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representative / fluorescence reporter / large fluorescence reporter / General / D.J. / /

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Bac / IC50 / Avatar / Molscript 2.1.2 / /

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Oregon / California / /

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NATURE CHEMICAL BIOLOGY / Molecular Biology / /

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alpha / Molecular modeling / DNA sequencing / directed mutagenesis / spectroscopy / drug design / FlAsH / CAT / /

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