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City CURRENT MEDICINE / Leiden / / Company APL / / Continent Europe / / Country Netherlands / France / Scotland / Guinea / United States / / Currency pence / / Facility Leiden University Medical Center / Glasgow University / Institute of Neurological Sciences / / IndustryTerm MS therapeutics / magnetic resonance imaging / MS therapies / final product / treatment of MS / Magnetic resonance imaging studies / breakdown products / / MedicalCondition namely hypertrophic peripheral neuropathy / MS. Experimental allergic encephalomyelitis / acute / infectious meningoencephalitis / viral infection / aphasia / Certain neurological diseases / chickenpox / perivenous inflammation / smallpox / neurodegenerative disease / Thyroid disease / complex disease / fibrinoid necrosis / rheumatoid arthritis / coma / secondary progressive disorder / prion disease / EAE Experimental allergic encephalomyelitis / inflammatory mediators / prototype disease / specific autoimmune diseases / e.g. infection / primary human demyelinating disease / spondylosis / immune deficiency / Multiple sclerosis / disorder / autoimmune disorder / often optic neuritis / illness / severe disease / chronic form / inflammatory diseases / autoimmune inflammatory condition / paralysis / namely malignant glioma / endotoxic shock / neurodegenerative and metabolic disorder / experimental autoimmune demyelinating disease / further demyelination / intensely aggressive inflammatory disorder / past decade multiple sclerosis / immunologically mediated disease / narcolepsy / Diabetes / fever / different demyelinating disorder / neurofibromatosis / acquired inflammatory disorder / vomiting / stupor / chronic disease / encephalitis / diseases / allergic reactions / certain viral infections / infection / neurofibromatosis-I / cerebral glioma / primary demyelinating diseases / Experimental Allergic Encephalomyelitis / such disorders / inflammatory / SUMMARY Multiple sclerosis / POSSIBLE AUTOIMMUNE DISEASE Histological findings Multiple sclerosis / allergic encephalomyelitis / mild monophasic clinical illness / headache / meningism / severe inflammatory disorders / encephalomyelitis / acute disseminated encephalomyelitis / rabies / chronic disorder / glioma / best studied organspecific experimental autoimmune diseases / inflammatory sites / monophasic disease / hind leg paralysis / gliotic scar / encephalopathy / mild disorder / demyelination / inflammatory cells / pre-existing viral infection / prototype primary demyelinating disease / demyelinating diseases / MS / both diseases / infections / metastatic brain tumours / neurodegenerative disorders / frank fibrinoid necrosis / myasthenia gravis / cervical spondylosis / autoimmune diseases / HIV infection / best studied organ-specific autoimmune disease / These diseases / disease / virulent disease / human demyelinating diseases / pertussis / glioblastoma multiforme / bilateral optic neuritis / tumour / unknown infectious agent / allergic encephalitis / hypertrophic peripheral neuropathy / common neurological disorders / inflammatory haematogenous / autoimmune disease / delirium / neurological diseases / inflammation / active demyelination / little ataxia / common human demyelinating disease / / MedicalTreatment vaccination / immunotherapy / radiation / plasma exchange / Immunosuppression / radiation therapy / Treatment protocols / lymphoid irradiation / immunosuppressive therapy / vaccinations / Total body irradiation / / Organization Department of Immunohaematology and Blood Bank / Leiden University Medical Center / Department of Neurology / Glasgow University / Institute of Neurological Sciences / MS Association / / Person Wilkinson / Wirguin / Charcot / B.O. Roep / Seitelberger / Jellinger / P.O. Behan / Guseo / Bertrand Russell / / Position Professor Emeritus / Associate Professor / Senior Lecturer / writer / animal model / i.e / / Product cyclosporine / Avonex / Repeated injections / azathioprine / cladribine / cyclophosphamide / sulfasalazine / Rebif / / ProvinceOrState Mississippi / / PublishedMedium The Charlestown Gazette / The Cochrane Review / / Technology radiation / magnetic resonance imaging / spectroscopy / antibodies / cloning / MRI / / SocialTag 
CURRENT MEDICINE THE PATHOGENESIS OF MULTIPLE SCLEROSIS REVISITED