oxyanion leaving / charge generation site / chemical shift changes / chemical character/reactivity / chemical reactivity / hydrolysis products / metal ion / ionization site / electrostatic potential energy decreases / hydroxy / chemical shift / electronic/chemical nature / cleavage products / model systems / chemical shift study / metal ion cofactor / chemical shifts / specific metal ion / chemical basis / pure cleavage products / high energy penalty / chemical reactivities / cleavage product / pH-dependent chemical shift / transesterification site / electrostatic potential energy / respective chemical reactivities / physico-chemical studies / metal ions / secondary hydrolysis products / chemical character / chemical shift data / model heptameric ssRNA systems / alkaline hydrolysis products / /
Organization
Biomedical Center / Royal Society of Chemistry / Department of Medical Biochemistry and Microbiology / Uppsala University / /
www.rsc.org/obc | Organic & Biomolecular Chemistry PAPER Non-identical electronic characters of the internucleotidic phosphates in RNA modulate the chemical reactivity of the phosphodiester bonds†‡