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TOPICAL IMMUNOMODULATOR CRITERIA Pharmacology: Pimecrolimus inhibits the calcium-dependent phosphatase (calcineurin), interfering with T-cell activation and transcription of early cytokines. Thus, it decreases the synthe
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Document Date: 2014-09-11 16:48:58
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TOPICAL IMMUNOMODULATOR CRITERIA Pharmacology: Pimecrolimus inhibits the calcium-dependent phosphatase (calcineurin), interfering with T-cell activation and transcription of early cytokines. Thus, it decreases the synthe